Pharmacotherapy of obesity: an update on the available medications and drugs under investigation

M Chakhtoura, R Haber, M Ghezzawi, C Rhayem… - …, 2023 - thelancet.com
Obesity is an epidemic and a public health threat. Medical weight management remains one
of the options for the treatment of excess weight and recent advances have revolutionized …

AGA clinical practice update on lifestyle modification using diet and exercise to achieve weight loss in the management of nonalcoholic fatty liver disease: expert …

ZM Younossi, KE Corey, JK Lim - Gastroenterology, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease, with
global public health impact affecting more than 25% of the global population. NAFLD is …

Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures–2019 update: cosponsored …

JI Mechanick, C Apovian, S Brethauer… - Surgery for Obesity and …, 2020 - Elsevier
Objective The development of these updated clinical practice guidelines (CPG) was
commissioned by the American Association of Clinical Endocrinologists, The Obesity …

Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2019 - Elsevier
The obesity epidemic is closely associated with the rising prevalence and severity of
nonalcoholic fatty liver disease (NAFLD): obesity has been linked not only with simple …

AGA clinical practice guideline on pharmacological interventions for adults with obesity

E Grunvald, R Shah, R Hernaez, AK Chandar… - Gastroenterology, 2022 - Elsevier
Background & Aims Pharmacological management of obesity improves outcomes and
decreases the risk of obesity-related complications. This American Gastroenterological …

NAFLD as a continuum: from obesity to metabolic syndrome and diabetes

AF Godoy-Matos, WS Silva Júnior… - Diabetology & metabolic …, 2020 - Springer
Background The prevalence of non-alcoholic fatty liver disease (NAFLD) has been
increasing rapidly. It is nowadays recognized as the most frequent liver disease, affecting a …

Efficacy and safety of endoscopic sleeve gastroplasty: a systematic review and meta-analysis

A Hedjoudje, BKA Dayyeh, LJ Cheskin, A Adam… - Clinical …, 2020 - Elsevier
Background & Aims Bariatric surgery is the most successful treatment for obesity. However,
many patients avoid surgery due to its perceived invasive nature and fear of complications …

Selection of antiobesity medications based on phenotypes enhances weight loss: a pragmatic trial in an obesity clinic

A Acosta, M Camilleri, B Abu Dayyeh, G Calderon… - …, 2021 - Wiley Online Library
Objective Little is known about the predictors of response to obesity interventions. Methods
In 450 participants with obesity, body composition, resting energy expenditure, satiety …

Adult obesity complications: challenges and clinical impact

S Ansari, H Haboubi… - Therapeutic advances in …, 2020 - journals.sagepub.com
The complications associated with adult obesity are overwhelming national healthcare
systems. No country has yet implemented a successful population-level strategy to reverse …

[HTML][HTML] Emerging pharmacotherapies for obesity: a systematic review

M Kokkorakis, M Chakhtoura, C Rhayem… - Pharmacological …, 2024 - Elsevier
The history of anti-obesity pharmacotherapies is marked by disappointments, often
entangled with societal pressure promoting weight loss and the prevailing conviction that …