Phosphatidylserine receptors enhance SARS-CoV-2 infection

D Bohan, H Van Ert, N Ruggio, KJ Rogers… - PLoS …, 2021 - journals.plos.org
Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through
virion-associated PS binding that is termed apoptotic mimicry. Here we show that this …

Receptors and cofactors that contribute to SARS-CoV-2 entry: can skin be an alternative route of entry?

M Barthe, L Hertereau, N Lamghari… - International Journal of …, 2023 - mdpi.com
To prevent the spread of SARS-CoV-2, all routes of entry of the virus into the host must be
mapped. The skin is in contact with the external environment and thus may be an alternative …

Designed ankyrin repeat proteins: a new class of viral entry inhibitors

M Walser, J Mayor, S Rothenberger - Viruses, 2022 - mdpi.com
Designed ankyrin repeat proteins (DARPins) are engineered proteins comprising
consensus designed ankyrin repeats as scaffold. Tightly packed repeats form a continuous …

Peptidomimetic oligomers targeting membrane phosphatidylserine exhibit broad antiviral activity

PM Tate, V Mastrodomenico, C Cunha… - ACS Infectious …, 2023 - ACS Publications
The development of durable new antiviral therapies is challenging, as viruses can evolve
rapidly to establish resistance and attenuate therapeutic efficacy. New compounds that …

Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens

R Groß, H Reßin, P von Maltitz, D Albers… - Nature …, 2024 - nature.com
Some viruses are rarely transmitted orally or sexually despite their presence in saliva, breast
milk, or semen. We previously identified that extracellular vesicles (EVs) in semen and saliva …

Cellular receptors for mammalian viruses

A Valero-Rello, C Baeza-Delgado… - Plos …, 2024 - journals.plos.org
The interaction of viral surface components with cellular receptors and other entry factors
determines key features of viral infection such as host range, tropism and virulence. Despite …

P34L mutation of swine TIM-1 enhances its ability to mediate Japanese encephalitis virus infection

W Jiao, S Xie, Z Liang, J Pan, X Yang, H Tong… - Veterinary …, 2022 - Elsevier
Japanese encephalitis virus (JEV) is a major causative agent of neurological infection
affecting humans and pigs. Human T Cell Immunoglobulin and Mucin Domain 1 (hTIM-1) …

[PDF][PDF] Designed Ankyrin Repeat Proteins: A New Class of Viral Entry Inhibitors. Viruses 2022, 14, 2242

M Walser, J Mayor, S Rothenberger - 2022 - serval.unil.ch
Designed ankyrin repeat proteins (DARPins) are engineered proteins comprising
consensus designed ankyrin repeats as scaffold. Tightly packed repeats form a continuous …

Estudio del control de la infección por virus VIH-1 y Zika: HDAC6 como factor antiviral en virus ARN+

S Pérez Yanes - 2023 - riull.ull.es
Los virus emergentes y reemergentes causan brotes epidémicos que representan crisis
globales impactando en la salud de las personas y, por tanto, en el desarrollo económico …

[PDF][PDF] Molecular Dynamics of Oligonucleotide DNA Complexes with Phosphatidylserine

MY Ibragimova, SY Zaitsev, RK Aupov, GV Andrianov… - 2022 - biointerfaceresearch.com
A formation of DNA-lipid complexes was studied by molec. docking and dynamics methods
using the interaction of DNA with phosphatidylserine (PS). We have previously shown that …