Chemotherapy is an essential treatment for breast cancer, inducing cancer cell death.
However, chemoresistance is a problem that limits the effectiveness of chemotherapy. Many …

Indication for neoadjuvant chemotherapy (NACT) in HR+/HER2-negative tumors is
controversial. Pathological complete response (pCR) rates range from 0 to 18% while breast …

Background As a natural compound extracted from a variety of hot peppers, capsaicin has
drawn increasing attention to its anti-cancer effects against multiple human cancers …

Breast cancer is the most prevalent cancer and the leading cause of cancer-related death
among women worldwide. Type 2 diabetes–associated metabolic traits such as …

The effect of polypyridyl Ru (II) complexes on the ability of cancer cells to migrate and
invade, two features important in the formation of metastases, is evaluated. In vitro studies …

Achieving a pathologic complete response after neoadjuvant treatment is associated with
improved prognosis in breast cancer. The CREATE-X trial demonstrated a significant …

Glioblastoma (GBM) tumor cells are found in the perivascular niche microenvironment and
are believed to associate closely with the brain microvasculature. However, it is largely …

Background Breast cancer clinical management requires the assessment of hormone
receptors (estrogen (ER) and progesterone receptor (PR)), human epidermal growth factor …

Rationale and Objectives This study aimed to create and verify a nomogram for preoperative
prediction of Ki-67 expression in breast malignancy to assist in the development of …

Introduction: Ki67 value and its variation before and after neoadjuvant chemotherapy are
commonly tested in relation to breast cancer patient prognosis. This study aims to quantify …