Drug-metabolizing cytochrome P450 enzymes have multifarious influences on treatment outcomes
Y Song, C Li, G Liu, R Liu, Y Chen, W Li, Z Cao… - Clinical …, 2021 - Springer
Drug metabolism is a critical process for the removal of unwanted substances from the body.
In humans, approximately 80% of oxidative metabolism and almost 50% of the overall …
In humans, approximately 80% of oxidative metabolism and almost 50% of the overall …
[HTML][HTML] Flavonoids from Aurantii Fructus Immaturus and Aurantii Fructus: promising phytomedicines for the treatment of liver diseases
J Wu, G Huang, Y Li, X Li - Chinese Medicine, 2020 - Springer
Background Liver diseases and related complications are major sources of morbidity and
mortality, which places a huge financial burden on patients and lead to nonnegligible social …
mortality, which places a huge financial burden on patients and lead to nonnegligible social …
[HTML][HTML] Insights into the mechanisms underlying efficient Rhizodegradation of PAHs in biochar-amended soil: From microbial communities to soil metabolomics
X Li, Y Song, Y Bian, C Gu, X Yang, F Wang… - Environment …, 2020 - Elsevier
The combined effects of biochar amendment and the rhizosphere on the soil metabolic
microbiome during the remediation of polycyclic aromatic hydrocarbon (PAH)-contaminated …
microbiome during the remediation of polycyclic aromatic hydrocarbon (PAH)-contaminated …
Arsenic or/and antimony induced mitophagy and apoptosis associated with metabolic abnormalities and oxidative stress in the liver of mice
G Zhong, F Wan, S Wu, X Jiang, Z Tang… - Science of the Total …, 2021 - Elsevier
Arsenic and antimony are coexisting cumulative environmental pollutants that cause severe
and extensive biological toxicity. However, their interactions and toxic mechanisms in the …
and extensive biological toxicity. However, their interactions and toxic mechanisms in the …
ONOO--triggered fluorescence H2S donor for mitigating drug-induced liver injury
J Liu, M Zhao, F Zhao, X Song, Y Ye - Sensors and Actuators B: Chemical, 2023 - Elsevier
Scavenging of toxic active substances (ROS and RNS) and releasing of protective H 2 S
may be a potential strategy to mitigate liver injury caused by clinical drugs. Hence, we …
may be a potential strategy to mitigate liver injury caused by clinical drugs. Hence, we …
[HTML][HTML] Auricularia auricula polysaccharides attenuate obesity in mice through gut commensal Papillibacter cinnamivorans
X Zong, H Zhang, L Zhu, EC Deehan, J Fu… - Journal of Advanced …, 2023 - Elsevier
Introduction Auricularia auricula is a well-known traditional edible and medical fungus with
high nutritional and pharmacological values, as well as metabolic and immunoregulatory …
high nutritional and pharmacological values, as well as metabolic and immunoregulatory …
The joint action of biochar and plant roots on U-stressed soil remediation: Insights from bacteriomics and metabolomics
N Li, Y Wang, L Zhou, D Fu, T Chen, X Chen… - Journal of Hazardous …, 2024 - Elsevier
Although biological remediation of U-stressed soil has been studied for a long time, the
combined effects of biochar and plant roots are rarely discussed and its influence on …
combined effects of biochar and plant roots are rarely discussed and its influence on …
Olanzapine-induced nonalcoholic fatty liver disease: the effects of differential food pattern and the involvement of PGRMC1 signaling
ZY Zhu, T Cao, H Chen, BK Zhang, CQ Lin… - Food and Chemical …, 2023 - Elsevier
Detrimental dietary habits with high-fat food are common in the psychiatric population,
leading to higher obesity rate. Olanzapine (OLZ), as one of the mainstream antipsychotic …
leading to higher obesity rate. Olanzapine (OLZ), as one of the mainstream antipsychotic …
Flavonoids-mediated SIRT1 signaling activation in hepatic disorders
The prevalence of various hepatic diseases increases dramatically worldwide and regarded
as a serious health problem. Sirtuins are one of the main strategic controllers of different …
as a serious health problem. Sirtuins are one of the main strategic controllers of different …
Metagenomics reveals mechanism of pyrene degradation by an enriched bacterial consortium from a coking site contaminated with PAHs
Q Wang, J Hou, Y Huang, W Liu, P Christie - Science of The Total …, 2023 - Elsevier
A bacterial consortium, termed WPB, was obtained from polycyclic aromatic hydrocarbons
(PAHs) contaminated soil from a coking site. The consortium effectively degraded 100 mg L …
(PAHs) contaminated soil from a coking site. The consortium effectively degraded 100 mg L …