Using PyMOL as a platform for computational drug design
PyMOL, a cross‐platform molecular graphics tool, has been widely used for three‐
dimensional (3D) visualization of proteins, nucleic acids, small molecules, electron …
dimensional (3D) visualization of proteins, nucleic acids, small molecules, electron …
[HTML][HTML] Engineering enzyme access tunnels
Enzymes are efficient and specific catalysts for many essential reactions in biotechnological
and pharmaceutical industries. Many times, the natural enzymes do not display the catalytic …
and pharmaceutical industries. Many times, the natural enzymes do not display the catalytic …
Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance
Emergent resistance to all clinical antibiotics calls for the next generation of therapeutics.
Here we report an effective antimicrobial strategy targeting the bacterial hydrogen sulfide …
Here we report an effective antimicrobial strategy targeting the bacterial hydrogen sulfide …
PDBsum: Structural summaries of PDB entries
PDBsum is a web server providing structural information on the entries in the Protein Data
Bank (PDB). The analyses are primarily image‐based and include protein secondary …
Bank (PDB). The analyses are primarily image‐based and include protein secondary …
Structures of the TMC-1 complex illuminate mechanosensory transduction
H Jeong, S Clark, A Goehring… - Nature, 2022 - nature.com
The initial step in the sensory transduction pathway underpinning hearing and balance in
mammals involves the conversion of force into the gating of a mechanosensory transduction …
mammals involves the conversion of force into the gating of a mechanosensory transduction …
A Novel Polyester Hydrolase From the Marine Bacterium Pseudomonas aestusnigri – Structural and Functional Insights
A Bollinger, S Thies, E Knieps-Grünhagen… - Frontiers in …, 2020 - frontiersin.org
Biodegradation of synthetic polymers, in particular polyethylene terephthalate (PET), is of
great importance, since environmental pollution with PET and other plastics has become a …
great importance, since environmental pollution with PET and other plastics has become a …
MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update)
MOLEonline is an interactive, web-based application for the detection and characterization
of channels (pores and tunnels) within biomacromolecular structures. The updated version …
of channels (pores and tunnels) within biomacromolecular structures. The updated version …
Caver Web 1.0: identification of tunnels and channels in proteins and analysis of ligand transport
Caver Web 1.0 is a web server for comprehensive analysis of protein tunnels and channels,
and study of the ligands' transport through these transport pathways. Caver Web is the first …
and study of the ligands' transport through these transport pathways. Caver Web is the first …
PDBsum additions
Abstract PDBsum, http://www. ebi. ac. uk/pdbsum, is a website providing numerous pictorial
analyses of each entry in the Protein Data Bank. It portrays the structural features of all …
analyses of each entry in the Protein Data Bank. It portrays the structural features of all …
Role of distal sites in enzyme engineering
J Gu, Y Xu, Y Nie - Biotechnology Advances, 2023 - Elsevier
The limitations associated with natural enzyme catalysis have triggered the rise of the field of
protein engineering. Traditional rational design was based on the analysis of protein …
protein engineering. Traditional rational design was based on the analysis of protein …