Cardiovascular diseases, the number 1 cause of death worldwide, are frequently associated
with apoptotic death of cardiac myocytes. Since cardiomyocyte apoptosis is a highly …

The discovery of ischemic postconditioning (IPost) has rejuvenated the field of
cardioprotection. As an interventional strategy to be applied at the onset of myocardial …

Mitochondria (MT) participate in most metabolic activities of mammalian cells. A near-
unidirectional mitochondrial transfer from T cells to cancer cells was recently observed to" …

Regular physical activity or exercise training can lead to heart enlargement known as
cardiac hypertrophy. Cardiac hypertrophy is broadly defined as an increase in heart mass. In …

Sublethal levels of oxidative stress are commonly associated with various
pathophysiological conditions. Cardiomyocytes have the highest content of mitochondria …

Objectives: The goal of this study was to demonstrate the enhancement of human cardiac
progenitor cell (hCPC) reparative and regenerative potential by genetic modification for the …

Mitochondrial morphological dynamics affect the outcome of ischemic heart damage and
pathogenesis. Recently, mitochondrial fission protein dynamin-related protein 1 (Drp1) has …

Rationale: Adoptive transfer of cardiac progenitor cells (CPCs) has entered clinical
application, despite limited mechanistic understanding of the endogenous response after …

Rationale: Myocardial function is enhanced by adoptive transfer of human cardiac
progenitor cells (hCPCs) into a pathologically challenged heart. However, advanced age …

Rationale: Studies in transgenic mice showed the key role of (Pim-1)(proviral integration site
for Moloney murine leukemia virus-1) in the control of cardiomyocyte function and viability …