Pathophysiology and treatment of septic shock in neonates

JL Wynn, HR Wong - Clinics in perinatology, 2010 - perinatology.theclinics.com
Sepsis or serious infection within the first 4 weeks of life kills more than 1 million newborns
globally every year. 1 The attack rate for neonatal sepsis is variable (from< 1% to> 35% of …

Role of innate host defenses in susceptibility to early-onset neonatal sepsis

JL Wynn, O Levy - Clinics in perinatology, 2010 - perinatology.theclinics.com
Infection claims the lives of approximately 3000 neonates worldwide every day. 1 Preterm
newborns are the most affected because they exhibit the highest sepsisrelated morbidity …

Hemostatic and fibrinolytic indices in neonatal foals with presumed septicemia

MH Barton, DD Morris, N Norton… - Journal of Veterinary …, 1998 - Wiley Online Library
Thirteen coagulation tests evaluating hemostatic and fibrinolytic indices and serum cytokine
and plasma endotoxin concentrations were obtained in 34 foals with a positive sepsis score …

Activation of the intrinsic pathway of coagulation in children with meningococcal septic shock

WA Wuillemin, K Fijnvandraat… - Thrombosis and …, 1995 - thieme-connect.com
Meningococcal septic shock (MSS) is complicated by activation of coagulation, fibrinolytic,
and complement systems. We studied the contact system of the intrinsic pathway of …

Neonatal sepsis in Karachi: factors determining outcome and mortality

ZA Bhutta, K Yusuf - Journal of tropical pediatrics, 1997 - academic.oup.com
Neonatal sepsis is a major cause of morbidity and mortality among newborns in the
developing world. In a consecutive cohort of 292 infants with culture proven neonatal sepsis …

Pathophysiology of neonatal sepsis

JL Wynn, HR Wong - Fetal and Neonatal Physiology, 2016 - pmc.ncbi.nlm.nih.gov
A successful immune response is critically necessary to eradicate infectious challenges and
prevent dissemination of the infection in the host. However, if inflammation is not limited and …

Plasma d‐Dimer Concentration in Sick Newborn Foals

L Armengou, L Monreal, I Tarancon… - Journal of veterinary …, 2008 - Wiley Online Library
Background: Septicemia is associated with a systemic inflammatory response, hemostatic
activation, and disseminated intravascular coagulopathy (DIC). Hypothesis: Increased …

Sepsis

JL Wynn, JA Hazelzet, TP Shanley, HR Wong… - Pediatric Critical Care …, 2014 - Springer
The management of the child with sepsis represents the sine qua non of pediatric critical
care medicine. Overwhelming sepsis and septic shock often manifest with concurrent …

Neonatal sepsis and hemostasis

D Gialamprinou, G Mitsiakos, GN Katsaras… - Diagnostics, 2022 - mdpi.com
Neonatal sepsis is considered critical for a significant increase in neonatal morbidity and
mortality among hospitalized neonates. Neonatal sepsis, in most cases, coexists with …

Coagulation and fibrinolytic systems in the ill preterm newborn

A Mautone, P Giordano, O Montagna… - Acta …, 1997 - Wiley Online Library
Aim: The activation pattern of the clotting and fibrinolytic systems in 63 preterm infants (GA
31, 6±2.3 weeks) was studied. Methods: The infants were divided into four groups:(i) …