The exponentially increasing use of hazardous traditional organic solvents and catalysts for
more accessible synthesis of important heterocycles useful for humankind in various fields …

Molecular hybridization is one of the recent strategies to synthesize a novel hybrid
compound by combining two or more pharmacophoric units. Being a linkage process, it …

This study employed a ligand-based pharmacophoric approach to design and synthesize 33
novel semisynthetic labdane-appended triazolyl isatins to discover potential anti …

The generation of heterocycles containing 1, 2, 3-triazole and pyrazole moieties has been
explored. The synthesis of these heterocycles is of interest because they are components of …

N-Heterocycles stand out in medicinal chemistry as significant pharmacophores because of
their wide biological potential and structural diversity. In this perspective, we have …

The adamantane moiety has attracted significant attention since its discovery in 1933 due to
its remarkable structural, chemical, and medicinal properties. This molecule has a notable …

In an effort to develop new antimicrobial and antibiofilm agents, we have designed and
synthesized a novel class of isatin-thiosemicarbazone-1, 2, 3-triazoles through the CuAAC …

With the aim to identify new antimicrobials, in the present study a new series of isatin based
1, 2, 3-triazoles (5a-5f & 6a-6f) has been synthesized through CuAAC click reaction and …

In the present work, a new class of thiazole‐isatin‐1, 2, 3‐triazole hybrids (5 a–5 p) and
precursor alkyne hybrids (6 a–6 d) has been reported with their in‐silico studies. After …

The development of novel antimicrobial drugs is crucial due to the increasing problem of
antibiotic resistance. A new series of 1, 4-disubstituted-1, 2, 3-triazole derivatives containing …