Diabetic retinopathy: pathogenic mechanisms and current treatments
DA Chistiakov - Diabetes & Metabolic Syndrome: Clinical Research & …, 2011 - Elsevier
Since diabetes is now a global epidemic, the incidence of retinopathy, a leading cause of
blindness in patients aged 20–74 years, is also expected to rise to alarming levels. The risk …
blindness in patients aged 20–74 years, is also expected to rise to alarming levels. The risk …
Diet and ideal food pyramid to prevent or support the treatment of diabetic retinopathy, age-related macular degeneration, and cataracts
M Rondanelli, C Gasparri, A Riva, G Petrangolini… - Frontiers in …, 2023 - frontiersin.org
Many eye diseases, such as diabetic retinopathy (DR), age-related macular degeneration
(AMD), and cataracts are preventable and treatable with lifestyle. The objective of this review …
(AMD), and cataracts are preventable and treatable with lifestyle. The objective of this review …
Synthesis of new clioquinol derivatives as potent α-glucosidase inhibitors; molecular docking, kinetic and structure–activity relationship studies
Diabetes mellitus is a chronic metabolic disorder with increasing prevalence and long-term
complications. The aim of this study was to identify α-glucosidase inhibitory compounds with …
complications. The aim of this study was to identify α-glucosidase inhibitory compounds with …
Complement activation in the vitreous of patients with proliferative diabetic retinopathy
N Mandava, V Tirado-Gonzalez… - … & visual science, 2020 - iovs.arvojournals.org
Purpose: A growing body of evidence points to complement dysregulation in diabetes. Early
studies have indicated the presence of complement components inside the eye in patients …
studies have indicated the presence of complement components inside the eye in patients …
Automated diabetic retinopathy grading using deep convolutional neural network
SS Chaturvedi, K Gupta, V Ninawe… - arXiv preprint arXiv …, 2020 - arxiv.org
Diabetic Retinopathy is a global health problem, influences 100 million individuals
worldwide, and in the next few decades, these incidences are expected to reach epidemic …
worldwide, and in the next few decades, these incidences are expected to reach epidemic …
Drug-like properties of tyrosine kinase inhibitors in ophthalmology: Formulation and topical availability
P Jansook, T Loftsson, E Stefánsson - International Journal of …, 2024 - Elsevier
Tyrosine kinase inhibitors (TKIs) can inhibit edema and neovascularization, such as in age-
related macular degeneration and diabetic retinopathy. However, their topical administration …
related macular degeneration and diabetic retinopathy. However, their topical administration …
Inhibition of aldose reductase by novel phytocompounds: A heuristic approach to treating diabetic retinopathy
A Julius, RR Renuka, W Hopper… - Evidence‐Based …, 2022 - Wiley Online Library
Aldose reductase (ALR2) activation in the polyol pathway has been implicated as the
primary mechanism for the progression of diabetic retinopathy. Most of the aldose reductase …
primary mechanism for the progression of diabetic retinopathy. Most of the aldose reductase …
Biomarkers in diabetic retinopathy and the therapeutic implications
K Zorena, D Raczyńska… - Mediators of …, 2013 - Wiley Online Library
The main problem both in type 1 (T1DM) and type 2 (T2DM) diabetes is the development of
chronic vascular complications encompassing micro‐as well as macrocirculation. Chronic …
chronic vascular complications encompassing micro‐as well as macrocirculation. Chronic …
Visual impairment and multimorbidity in a representative sample of the Spanish population
Background In the context of population aging, visual impairment has emerged as a growing
concern in public health. However, there is a need for further research into the relationship …
concern in public health. However, there is a need for further research into the relationship …
Association of increased levels of MCP-1 and cathepsin-D in young onset type 2 diabetes patients (T2DM-Y) with severity of diabetic retinopathy
Aim Young onset type 2 diabetes patients (T2DM-Y) have been shown to possess an
increased risk of developing microvascular complications particularly diabetic retinopathy …
increased risk of developing microvascular complications particularly diabetic retinopathy …