Extracellular vesicles as an efficient and versatile system for drug delivery
Despite the recent advances in drug development, the majority of novel therapeutics have
not been successfully translated into clinical applications. One of the major factors hindering …
not been successfully translated into clinical applications. One of the major factors hindering …
ITGB3-mediated uptake of small extracellular vesicles facilitates intercellular communication in breast cancer cells
P Fuentes, M Sesé, PJ Guijarro, M Emperador… - Nature …, 2020 - nature.com
Metastasis, the spread of malignant cells from a primary tumour to distant sites, causes 90%
of cancer-related deaths. The integrin ITGB3 has been previously described to play an …
of cancer-related deaths. The integrin ITGB3 has been previously described to play an …
Alternative biological sources for extracellular vesicles production and purification strategies for process scale-up
S Giancaterino, C Boi - Biotechnology Advances, 2023 - Elsevier
Extracellular vesicles (EVs) are phospholipidic bi-layer enclosed nanoparticles secreted
naturally by all cell types. They are attracting increasing attention in the fields of …
naturally by all cell types. They are attracting increasing attention in the fields of …
Engineered exosomes for studies in tumor immunology
A Alptekin, M Parvin, HI Chowdhury… - Immunological …, 2022 - Wiley Online Library
Exosomes are a type of extracellular vesicle (EV) with diameters of 30–150 nm secreted by
most of the cells into the extracellular spaces and can alter the microenvironment through …
most of the cells into the extracellular spaces and can alter the microenvironment through …
Identifying extracellular vesicle populations from single cells
JM Nikoloff, MA Saucedo-Espinosa… - Proceedings of the …, 2021 - National Acad Sciences
Extracellular vesicles (EVs) are constantly secreted from both eukaryotic and prokaryotic
cells. EVs, including those referred to as exosomes, may have an impact on cell signaling …
cells. EVs, including those referred to as exosomes, may have an impact on cell signaling …
Microvesicles in cancer: Small size, large potential
K Menck, S Sivaloganathan, A Bleckmann… - International journal of …, 2020 - mdpi.com
Extracellular vesicles (EV) are secreted by all cell types in a tumor and its microenvironment
(TME), playing an essential role in intercellular communication and the establishment of a …
(TME), playing an essential role in intercellular communication and the establishment of a …
Surface protein profiling of milk and serum extracellular vesicles unveils body fluid-specific signatures
A Giovanazzi, MJC van Herwijnen, M Kleinjan… - Scientific Reports, 2023 - nature.com
Cell-derived extracellular vesicles (EVs) are currently in the limelight as potential disease
biomarkers. The promise of EV-based liquid biopsy resides in the identification of specific …
biomarkers. The promise of EV-based liquid biopsy resides in the identification of specific …
Harnessing extracellular vesicle heterogeneity for diagnostic and therapeutic applications
Extracellular vesicles (EVs) are diverse nanoparticles with large heterogeneity in size and
molecular composition. Although this heterogeneity provides high diagnostic value for liquid …
molecular composition. Although this heterogeneity provides high diagnostic value for liquid …
Emerging technologies for profiling extracellular vesicle heterogeneity
Extracellular vesicles (EVs) are membrane-bound vesicles secreted by most cell types and
exist in virtually all bodily fluids. They carry on a wealth of proteomic and genetic information …
exist in virtually all bodily fluids. They carry on a wealth of proteomic and genetic information …
Extracellular vesicles and oncogenic signaling
A Schubert, M Boutros - Molecular oncology, 2021 - Wiley Online Library
In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic
markers for cancer therapy. While the field of EV research is rapidly developing and their …
markers for cancer therapy. While the field of EV research is rapidly developing and their …