Tissue-Nonspecific alkaline Phosphatase—A gatekeeper of physiological conditions in health and a modulator of biological environments in disease
Tissue-nonspecific alkaline phosphatase (TNAP) is a ubiquitously expressed enzyme that is
best known for its role during mineralization processes in bones and skeleton. The enzyme …
best known for its role during mineralization processes in bones and skeleton. The enzyme …
Orthophosphate and alkaline phosphatase induced the formation of apatite with different multilayered structures and mineralization balance
Mineralized collagen is a natural organic–inorganic composite. The combination of organic
collagen and inorganic apatite to form different nanostructures is the key to producing bone …
collagen and inorganic apatite to form different nanostructures is the key to producing bone …
Bone turnover and mineral metabolism in adult patients with hypophosphatasia treated with asfotase alfa
L Seefried, D Rak, A Petryk, F Genest - Osteoporosis International, 2021 - Springer
There is limited understanding of how asfotase alfa affects mineral metabolism and bone
turnover in adults with pediatric-onset hypophosphatasia. This study showed that adults with …
turnover in adults with pediatric-onset hypophosphatasia. This study showed that adults with …
Fluorescence attenuated by a thick scattering medium: theory, simulations and experiments
Fluorescence‐based imaging has an enormous impact on our understanding of biological
systems. However, in vivo fluorescence imaging is greatly influenced by tissue scattering. A …
systems. However, in vivo fluorescence imaging is greatly influenced by tissue scattering. A …
Gene Therapy Using Adeno‐Associated Virus Serotype 8 Encoding TNAP‐D10 Improves the Skeletal and Dentoalveolar Phenotypes in Alpl−/− Mice
Y Kinoshita, FF Mohamed… - Journal of Bone and …, 2020 - academic.oup.com
Hypophosphatasia (HPP) is caused by loss‐of‐function mutations in the ALPL gene that
encodes tissue‐nonspecific alkaline phosphatase (TNAP), whose deficiency results in the …
encodes tissue‐nonspecific alkaline phosphatase (TNAP), whose deficiency results in the …
Massive calcification around large joints in a patient subsequently diagnosed with adult-onset hypophosphatasia
We report a 64-year-old Japanese woman with a history of progressive loss of motor
function and painful swelling of large joints. At the age of 54, profound calcification appeared …
function and painful swelling of large joints. At the age of 54, profound calcification appeared …
[PDF][PDF] PROSPECTS FOR THE USE OF PATHOLOGICAL BIOMINERALIZATION IN THE DIAGNOSIS OF OVARIAN CANCER
R Chyzhma, R Moskalenko - Publishing House “Baltija …, 2023 - baltijapublishing.lv
Ovarian cancer is one of the most common causes of death in the female population. Among
malignant tumors, ovarian cancer ranks fourth after neoplasms of the body, cervix, and …
malignant tumors, ovarian cancer ranks fourth after neoplasms of the body, cervix, and …