[HTML][HTML] Serum amyloid A–a review
GH Sack Jr - Molecular medicine, 2018 - Springer
Serum amyloid A (SAA) proteins were isolated and named over 50 years ago. They are
small (104 amino acids) and have a striking relationship to the acute phase response with …
small (104 amino acids) and have a striking relationship to the acute phase response with …
Cellular and molecular mechanisms of chronic obstructive pulmonary disease
PJ Barnes - Clinics in chest medicine, 2014 - chestmed.theclinics.com
Chronic obstructive pulmonary disease (COPD) involves chronic inflammation of the lung,
particularly in peripheral airways and parenchyma, which increases during acute …
particularly in peripheral airways and parenchyma, which increases during acute …
[HTML][HTML] Role of IL-6 in asthma and other inflammatory pulmonary diseases
The incidence and severity of chronic lung diseases is growing and affects between 100 and
150 million people worldwide and is associated with a significant rate of mortality …
150 million people worldwide and is associated with a significant rate of mortality …
[HTML][HTML] Comorbidity, systemic inflammation and outcomes in the ECLIPSE cohort
J Miller, LD Edwards, A Agustí, P Bakke… - Respiratory …, 2013 - Elsevier
Comorbidities, are common in COPD, have been associated with poor outcomes and are
thought to relate to systemic inflammation. To investigate comorbidities in relation to …
thought to relate to systemic inflammation. To investigate comorbidities in relation to …
Systemic manifestations and comorbidities of COPD
Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is a
complex disease involving more than airflow obstruction. Airflow obstruction has profound …
complex disease involving more than airflow obstruction. Airflow obstruction has profound …
[HTML][HTML] Understanding the role of neutrophils in chronic inflammatory airway disease
Airway neutrophilia is a common feature of many chronic inflammatory lung diseases and is
associated with disease progression, often regardless of the initiating cause. Neutrophils …
associated with disease progression, often regardless of the initiating cause. Neutrophils …
[HTML][HTML] COPD exacerbations: defining their cause and prevention
JA Wedzicha, TAR Seemungal - The lancet, 2007 - thelancet.com
Exacerbations of chronic obstructive pulmonary disease (COPD) are episodes of worsening
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …
of symptoms, leading to substantial morbidity and mortality. COPD exacerbations are …
Sarcopenia correlates with systemic inflammation in COPD
MK Byun, EN Cho, J Chang, CM Ahn… - International journal of …, 2017 - Taylor & Francis
Background Muscle wasting and chronic inflammation are predominant features of patients
with COPD. Systemic inflammation is associated with an accelerated decline in lung …
with COPD. Systemic inflammation is associated with an accelerated decline in lung …
Increased risk of myocardial infarction and stroke following exacerbation of COPD
GC Donaldson, JR Hurst, CJ Smith, RB Hubbard… - Chest, 2010 - Elsevier
Objective Patients with COPD are at risk for cardiovascular events. This is attributed to
increased systemic inflammation. The course of COPD is punctuated by exacerbations …
increased systemic inflammation. The course of COPD is punctuated by exacerbations …
Outcomes for COPD pharmacological trials: from lung function to biomarkers
M Cazzola, W MacNee, FJ Martinez… - European respiratory …, 2008 - Eur Respiratory Soc
The American Thoracic Society/European Respiratory Society jointly created a Task Force
on “Outcomes for COPD pharmacological trials: from lung function to biomarkers” to inform …
on “Outcomes for COPD pharmacological trials: from lung function to biomarkers” to inform …