Glial cells constitute without any dispute an essential element in providing an efficiently
operating nervous system. Work in many labs over the last decades has demonstrated that …

Glia play a crucial role in providing metabolic support to neurons across different species. To
do so, glial cells isolate distinct neuronal compartments from systemic signals and …

Intellectual disability (ID) disorders are genetically and phenotypically extremely
heterogeneous. Can this complexity be depicted in a comprehensive way as a means of …

Neuronal information processing requires a large amount of energy, indicating that sugars
and other metabolites must be efficiently delivered. However, reliable neuronal function also …

The invertebrate blood-brain barrier (BBB) field is growing at a rapid pace and, in recent
years, studies have shown a physiologic and molecular complexity that has begun to rival its …

Glia are important modulators of neural activity, yet few studies link glia to sleep regulation.
We find that blocking activity of the endocytosis protein, dynamin, in adult Drosophila glia …

Highlights•Drosophila glia share many properties with their mammalian
counterparts.•Different subpopulations of glia cells cooperate to support neuronal energy …

The specification and adaptability of cells rely on changes in protein composition.
Nonetheless, uncovering proteome dynamics with cell-type-specific resolution remains …

We designed a novel imaging technique based on frustrated total internal reflection (FTIR) to
obtain high resolution and high contrast movies. This F TIR-based I maging M ethod (FIM) is …

Hereditary spastic paraplegia (HSP) is a set of genetic diseases caused by mutations in one
of 72 genes that results in age-dependent corticospinal axon degeneration accompanied by …