Prostate cancer is the second most frequent cancer diagnosis made in men and the fifth
leading cause of death worldwide. Prostate cancer may be asymptomatic at the early stage …

Solid cancers are one of the leading causes of cancer related deaths, characterized by rapid
growth of tumour, and local and distant metastases. Current advances on multimodality care …

Background: Prostate-specific antigen (PSA) testing is the primary method used to diagnose
prostate cancer in the United States. Methods to integrate other risk factors associated with …

Background Sex hormones in serum have been hypothesized to influence the risk of
prostate cancer. We performed a collaborative analysis of the existing worldwide …

Prostate cancer is one of the most common types of cancer affecting men worldwide;
however, its etiology and pathological mechanisms remain poorly understood. Mechanical …

Background Prostate cancer is one of the most prevalent cancers in men. Exposure to heavy
metals and their association with prostate cancer risk has been studied extensively, but …

Background: Some, but not all, published results have shown an association between
circulating blood levels of some insulin-like growth factors (IGFs) and their binding proteins …

CONTEXT: More than half the male population aged> 50 yr have histologic evidence of
benign prostatic hyperplasia (BPH), while prostate cancer (PCa) is among the most common …

Metastatic disease is the principal cause of prostate-cancer-related mortality. Our ability to
accurately recapitulate the spread of prostate cancer to bone—the most common site of …

The incidence of prostate cancer continues to increase in the US. Compared with other
common cancers such as those of the breast and lung, the causes of prostate cancer remain …