Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications

R Garcia - Chemical Society Reviews, 2020 - pubs.rsc.org
Fast, high-resolution, non-destructive and quantitative characterization methods are needed
to develop materials with tailored properties at the nanoscale or to understand the …

Measuring viscoelasticity of soft biological samples using atomic force microscopy

YM Efremov, T Okajima, A Raman - Soft matter, 2020 - pubs.rsc.org
Mechanical properties play important roles at different scales in biology. At the level of a
single cell, the mechanical properties mediate mechanosensing and mechanotransduction …

Investigating cell mechanics with atomic force microscopy

K Haase, AE Pelling - Journal of The Royal Society …, 2015 - royalsocietypublishing.org
Transmission of mechanical force is crucial for normal cell development and functioning.
However, the process of mechanotransduction cannot be studied in isolation from cell …

Surveying membrane landscapes: a new look at the bacterial cell surface

T Lithgow, CJ Stubenrauch, MPH Stumpf - Nature Reviews Microbiology, 2023 - nature.com
Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …

The emergence of multifrequency force microscopy

R Garcia, ET Herruzo - Nature nanotechnology, 2012 - nature.com
In atomic force microscopy a cantilever with a sharp tip attached to it is scanned over the
surface of a sample, and information about the surface is extracted by measuring how the …

Imaging beyond the surface region: Probing hidden materials via atomic force microscopy

A Farokh Payam, A Passian - Science Advances, 2023 - science.org
Probing material properties at surfaces down to the single-particle scale of atoms and
molecules has been achieved, but high-resolution subsurface imaging remains a …

Measuring nanoscale viscoelastic parameters of cells directly from AFM force-displacement curves

YM Efremov, WH Wang, SD Hardy, RL Geahlen… - Scientific reports, 2017 - nature.com
Abstract Force-displacement (FZ) curves are the most commonly used Atomic Force
Microscopy (AFM) mode to measure the local, nanoscale elastic properties of soft materials …

Bacterial-nanostructure interactions: The role of cell elasticity and adhesion forces

A Elbourne, J Chapman, A Gelmi, D Cozzolino… - Journal of Colloid and …, 2019 - Elsevier
The attachment of single-celled organisms, namely bacteria and fungi, to abiotic surfaces is
of great interest to both the scientific and medical communities. This is because the …

Atomic force microscopy-based characterization and design of biointerfaces

D Alsteens, HE Gaub, R Newton… - Nature Reviews …, 2017 - nature.com
Atomic force microscopy (AFM)-based methods have matured into a powerful nanoscopic
platform, enabling the characterization of a wide range of biological and synthetic …

Fast nanomechanical spectroscopy of soft matter

ET Herruzo, AP Perrino, R Garcia - Nature communications, 2014 - nature.com
A method that combines high spatial resolution, quantitative and non-destructive mapping of
surfaces and interfaces is a long standing goal in nanoscale microscopy. The method would …