Objectives To evaluate the effectiveness of practices used to support appropriate clinical
laboratory test utilization. Methods This review followed the Centers for Disease Control and …

Cardiac biomarker testing is estimated to occur in nearly 30 million emergency department
visits nationwide each year in the United States. The American College of …

Transitions in medicine often are difficult especially when they involve diagnostic methods
that are used widely. Clinicians may find some of the new tools hard to understand …

Abstract Background The American Board of Internal Medicine Foundation's Choosing
Wisely campaign has resulted in a vast number of recommendations to reduce low-value …

Background Various combinations of creatine kinase‐MB, myoglobin, and cardiac troponin I
or T (cTnI/cTnT) have been used to evaluate patients with suspected acute coronary …

Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the
development of acute coronary syndrome (ACS). However, alterations of Lp-PLA2 levels …

Background The negative impact of unnecessary diagnostic tests on healthcare systems
and patients has been widely recognized. Medical researchers in various countries have …

Background Despite the high sensitivity and negative predictive value of contemporary high-
sensitivity troponin T assays (hsTnT), creatine kinase (CK) continues to be routinely tested …

BACKGROUND Identifying hospitals that are both early and consistent adopters of high‐
value care can help shed light on the culture and practices at those institutions that are …

Laboratory data are critical to analyzing and improving clinical quality. In the setting of
residual use of creatine kinase M and B isoenzyme testing for myocardial infarction, we …