A genetic basis of congenital isolated hypogonadotropic hypogonadism (CHH) can be
defined in almost 50% of cases, albeit not necessarily the complete genetic basis. Next …

Proper patterning of the nervous system requires that developing axons find appropriate
postsynaptic partners; this entails microns to meters of extension through an extracellular …

As the nervous system develops, newly differentiated neurons need to extend their axons
toward their synaptic targets to form functional neural circuits. During this highly dynamic …

Peripheral nerve regeneration and functional recovery remain a major clinical challenge.
Nerve guidance conduit (NGC) that can regulate biological behavior of Schwann cells (SCs) …

Class III β-tubulin (βIII-tubulin) is frequently overexpressed in human tumors and is
associated with resistance to microtubule-targeting agents, tumor aggressiveness, and poor …

Bisphenol A (BPA) and its derivatives, including bisphenols S (BPS), F (BPF), E (BPE), B
(BPB), Z (BPZ), and AF (BPAF), are widely used in consumer products. Moreover, they are …

The establishment of neuronal connectivity relies on the microtubule (MT) cytoskeleton,
which provides mechanical support, roads for axonal transport and mediates signalling …

During the establishment of neural circuitry axons often need to cover long distances to
reach remote targets. The stereotyped navigation of these axons defines the connectivity …

The neuronal cytoskeleton performs incredible feats during nervous system development.
Extension of neuronal processes, migration, and synapse formation rely on the proper …

Temporospatial regulation of guidance signaling is essential for axon outgrowth and
pathfinding in the developing nervous system. Regulation of Robo1 levels in commissural …