Sarcopenia is a geriatric disorder characterized by a progressive decline in muscle mass
and function. This disorder has been associated with a range of adverse health outcomes …

The age-related decline in skeletal muscle mass, strength and function known as
'sarcopenia'is associated with multiple adverse health outcomes, including cardiovascular …

Several recent studies suggest that obesity may be a risk factor for fracture. The aim of this
study was to investigate the association between body mass index (BMI) and future fracture …

Abstract The ACTN3 R577X (rs1815739) genotype has been associated with athletic status
and muscle phenotypes, although not consistently. Our objective was to conduct a meta …

The loss of muscle strength and increased injury rate in aging skeletal muscle has
previously been attributed to loss of muscle protein (cross-sectional area) and/or decreased …

Western populations are living longer. Ageing decline in muscle mass and strength (ie
sarcopenia) is becoming a growing public health problem, as it contributes to the decreased …

Genetic variation of the human ACE I/D and ACTN3 R577X polymorphisms subsequent to
12 weeks of high-speed power training on maximal strength (1RM) of the arm and leg …

Background Pompe's disease is a progressive myopathy caused by mutations in the
lysosomal enzyme acid alphaglucosidase gene (GAA). A wide clinical variability occurs also …

Osteoporosis is the most common multifactorial metabolic bone disorder worldwide with a
strong genetic component. In this review, the evidence for a genetic contribution to …

Both extrinsic and intrinsic factors predispose older people to fall. We performed a genome-
wide association analysis to investigate how much of an individual's fall susceptibility can be …