Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C (ut) annabinoid” System
The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …
homeostatic regulator, which influences a wide-variety of physiological processes all over …
[图书][B] Endocannabinoids and their pharmacological actions
RG Pertwee - 2015 - Springer
The endocannabinoid system consists of G protein-coupled cannabinoid CB 1 and CB 2
receptors, of endogenous compounds known as endocannabinoids that can target these …
receptors, of endogenous compounds known as endocannabinoids that can target these …
[图书][B] Melatoninergic system in the skin
Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …
Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes
The endocannabinoid system (ECS) regulates multiple physiological processes, including
cutaneous cell growth and differentiation. Here, we explored the effects of the major …
cutaneous cell growth and differentiation. Here, we explored the effects of the major …
Therapeutic potential of cannabidiol (CBD) for skin health and disorders
SM Baswan, AE Klosner, K Glynn… - Clinical, cosmetic and …, 2020 - Taylor & Francis
Though there is limited research confirming the purported topical benefits of cannabinoids, it
is certain that cutaneous biology is modulated by the human endocannabinoid system …
is certain that cutaneous biology is modulated by the human endocannabinoid system …
Transient receptor potential (TRP) channels: a clinical perspective
Y Kaneko, A Szallasi - British journal of pharmacology, 2014 - Wiley Online Library
Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
Transient receptor potential channels as therapeutic targets
MM Moran, MA McAlexander, T Bíró… - Nature reviews Drug …, 2011 - nature.com
Transient receptor potential (TRP) cation channels have been among the most aggressively
pursued drug targets over the past few years. Although the initial focus of research was on …
pursued drug targets over the past few years. Although the initial focus of research was on …
Why do cannabinoid receptors have more than one endogenous ligand?
V Di Marzo, L De Petrocellis - … Transactions of the …, 2012 - royalsocietypublishing.org
The endocannabinoid system was revealed following the understanding of the mechanism
of action of marijuana's major psychotropic principle, Δ 9-tetrahydrocannabinol, and …
of action of marijuana's major psychotropic principle, Δ 9-tetrahydrocannabinol, and …
Beyond neuronal heat sensing: diversity of TRPV1 heat-capsaicin receptor-channel functions
YM Shuba - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Transient receptor potential vanilloid 1 (TRPV1) is a calcium-permeable ion channel best
known for its ability to be gated by the pungent constituent of red chili pepper, capsaicin, and …
known for its ability to be gated by the pungent constituent of red chili pepper, capsaicin, and …
Bioactive lipid mediators in skin inflammation and immunity
AC Kendall, A Nicolaou - Progress in lipid research, 2013 - Elsevier
The skin is the primary barrier from the outside environment, protecting the host from injury,
infectious pathogens, water loss and solar ultraviolet radiation. In this role, it is supported by …
infectious pathogens, water loss and solar ultraviolet radiation. In this role, it is supported by …