ALS: A bucket of genes, environment, metabolism and unknown ingredients

M Zufiria, FJ Gil-Bea, R Fernandez-Torron… - Progress in …, 2016 - Elsevier
The scientific scenario of amyotrophic lateral sclerosis (ALS) has dramatically changed
since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal …

[HTML][HTML] A meta-analysis on alcohol drinking and gastric cancer risk

I Tramacere, E Negri, C Pelucchi, V Bagnardi, M Rota… - Annals of oncology, 2012 - Elsevier
Background Whether an association between alcohol drinking and gastric cancer risk exists
is an open question. In order to provide a definite quantification of the association between …

Cigarette smoking and gastric cancer in the Stomach Cancer Pooling (StoP) Project

D Praud, M Rota, C Pelucchi, P Bertuccio… - European Journal of …, 2018 - journals.lww.com
Tobacco smoking is a known cause of gastric cancer, but several aspects of the association
remain imprecisely quantified. We examined the relation between cigarette smoking and the …

Population differences in major functional polymorphisms of pharmacokinetics/pharmacodynamics-related genes in Eastern Asians and Europeans: implications in …

K Kurose, E Sugiyama, Y Saito - Drug metabolism and …, 2012 - jstage.jst.go.jp
Drug lag, recently discussed extensively in Japan, can be divided into two phases: clinical
development time and application review time. The former factor is still an important problem …

Nature meets nurture: molecular genetics of gastric cancer

AN Milne, F Carneiro, C O'morain, GJA Offerhaus - Human genetics, 2009 - Springer
The immensity of genes and molecules implicated in gastric carcinogenesis is
overwhelming and the relevant importance of some of these molecules is too often unclear …

Smoking, alcohol consumption, and the risk of amyotrophic lateral sclerosis: a population-based study

SW De Jong, MHB Huisman, NA Sutedja… - American journal of …, 2012 - academic.oup.com
Smoking has been posited as a possible risk factor for amyotrophic lateral sclerosis (ALS),
but large population-based studies of patients with incident disease are still needed. The …

Alcohol consumption and risk of stomach cancer: a meta-analysis

W Deng, L Jin, H Zhuo, V Vasiliou, Y Zhang - Chemico-Biological …, 2021 - Elsevier
Stomach cancer is one of the most common cancers in the world. The relationship between
alcohol consumption and the risk of stomach cancer remains unclear. Epidemiology studies …

Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium

G Martimianaki, G Alicandro, C Pelucchi… - British journal of …, 2022 - nature.com
Background Evidence from epidemiological studies on the role of tea drinking in gastric
cancer risk remains inconsistent. We aimed to investigate and quantify the relationship …

Polymorphisms of human N-acetyltransferases and cancer risk

JAG Agundez - Current drug metabolism, 2008 - ingentaconnect.com
Human arylamine N-acetyltransferases (CoASAc; NAT, EC 2.3. 1.5) NAT1 and NAT2 play a
key role in the metabolism of drugs and environmental chemicals and in the metabolic …

[HTML][HTML] Molecular alterations in gastric cancer with special reference to the early-onset subtype

M Skierucha, ANA Milne, GJA Offerhaus… - World journal of …, 2016 - ncbi.nlm.nih.gov
Currently, gastric cancer (GC) is one of the most frequently diagnosed neoplasms, with a
global burden of 723000 deaths in 2012. It is the third leading cause of cancer-related death …