Candida auris Genetics and Emergence
A Chowdhary, K Jain, N Chauhan - Annual Review of …, 2023 - annualreviews.org
Candida auris is a multidrug-resistant fungal pathogen that presents a serious threat to
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
global human health. Since the first reported case in 2009 in Japan, C. auris infections have …
Multidrug resistance in mammals and fungi—from MDR to PDR: a rocky road from atomic structures to transport mechanisms
N Khunweeraphong, K Kuchler - International journal of molecular …, 2021 - mdpi.com
Multidrug resistance (MDR) can be a serious complication for the treatment of cancer as well
as for microbial and parasitic infections. Dysregulated overexpression of several members of …
as for microbial and parasitic infections. Dysregulated overexpression of several members of …
Directed evolution detects supernumerary centric chromosomes conferring resistance to azoles in Candida auris
Candida auris exhibits resistance to multiple antifungal drug classes and sterilization
agents, posing threats to the immunocompromised worldwide. Among the four major …
agents, posing threats to the immunocompromised worldwide. Among the four major …
[HTML][HTML] Psychogenetic, genetic and epigenetic mechanisms in Candida auris: Role in drug resistance
In recent years, we are facing the challenge of drug resistance emergence in fungi. The
availability of limited antifungals and development of multi-drug resistance in fungal …
availability of limited antifungals and development of multi-drug resistance in fungal …
[HTML][HTML] Native human and mouse skin infection models to study Candida auris-host interactions
S Seiser, H Arzani, T Ayub, T Phan-Canh, C Staud… - Microbes and …, 2024 - Elsevier
Abstract The World Health Organization (WHO) declared certain fungal pathogens as global
health threats for the next decade. Candida auris (C. auris) is a newly emerging skin-tropic …
health threats for the next decade. Candida auris (C. auris) is a newly emerging skin-tropic …
Bibliometric analysis and thematic review of Candida pathogenesis: Fundamental omics to applications as potential antifungal drugs and vaccines
Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …
elevating global mortality. The pathogenicity of Candida spp. is not only originated from its …
Phenotypic and genetic features of a novel clinically isolated rough morphotype Candida auris
S Tian, J Bing, Y Chu, H Li, Q Wang, S Cheng… - Frontiers in …, 2023 - frontiersin.org
Introduction Candida auris is a newly emerging pathogenic fungus of global concern and
has been defined by the World Health Organization (WHO) as a member of the critical group …
has been defined by the World Health Organization (WHO) as a member of the critical group …
Transcriptomics and phenotyping define genetic signatures associated with echinocandin resistance in Candida auris
S Jenull, R Shivarathri, I Tsymala, P Penninger… - Mbio, 2022 - Am Soc Microbiol
Candida auris emerged as a human fungal pathogen only during the past decade.
Remarkably, C. auris displays high degrees of genomic diversity and phenotypic plasticity …
Remarkably, C. auris displays high degrees of genomic diversity and phenotypic plasticity …
Sphingolipid diversity in Candida auris: unraveling interclade and drug resistance fingerprints
In this study, we explored the sphingolipid (SL) landscape in Candida auris, which plays
pivotal roles in fungal biology and drug susceptibility. The composition of SLs exhibited …
pivotal roles in fungal biology and drug susceptibility. The composition of SLs exhibited …
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids
A Jallet, A Friedrich, J Schacherer - G3: Genes, Genomes …, 2023 - academic.oup.com
Gene expression variation can provide an overview of the changes in regulatory networks
that underlie phenotypic diversity. Certain evolutionary trajectories such as polyploidization …
that underlie phenotypic diversity. Certain evolutionary trajectories such as polyploidization …