Background Neurological diseases seriously affect human health, which are arousing wider
attention, and it is a great challenge to discover neuroprotective drugs with minimal side …

Growth-associated protein-43 (GAP-43) and brain acid-soluble protein 1 (BASP1) regulate
actin dynamics and presynaptic vesicle cycling at axon terminals, thereby facilitating axonal …

It is currently unclear how amyloid-β and tau deposition are linked to changes in synaptic
function and axonal structure over the course of Alzheimer's disease. Here, we assessed …

An account of the neurobiology of motor recovery in the arm and hand after stroke by two
experts in the field. Stroke is a leading cause of disability in adults and recovery is often …

Stroke is the leading cause of adult disability. Yet there is a limited degree of recovery in this
disease. One of the mechanisms of recovery is the formation of new connections in the brain …

Introduction The level of the presynaptic protein growth‐associated protein 43 (GAP‐43) in
cerebrospinal fluid (CSF) has previously been shown to be increased in Alzheimer's disease …

In a number of animal species, the growth-associated protein (GAP), GAP-43 (aka: F1,
neuromodulin, B-50, G50, pp46), has been implicated in the regulation of presynaptic …

Spinal muscular atrophy (SMA) is a neurodegenerative disease primarily affecting spinal
motor neurons. It is caused by reduced levels of the survival of motor neuron (SMN) protein …

The astrocyte, one of the glial cells, plays many functional roles. These include provision of
nutrients from blood vessels to neurons, supply of neurotransmitters and support of blood …

Stroke instigates regenerative responses that reorganize connectivity patterns among
surviving neurons. The new connectivity patterns can be suboptimal for behavioral function …