The central nervous system responds to diverse neurologic injuries with a vigorous
activation of astrocytes. While this phenomenon is found in many different species, its …

Human immunodeficiency virus type 1 (HIV‐1) infection of the central nervous system is
associated with characteristic virological, clinical, and neuropathological findings in adults …

Human immunodeficiency virus (HIV) infection of brain macrophages and astroglial
proliferation are central features of HIV-induced central nervous system (CNS) disorders …

Cytokines may play a pathogenetic role in the brain. Using human fetal brain cell cultures,
we investigated whether cytokines released during inflammation modulate neuronal injury …

The mechanism (s) by which HIV-1 affects neural injury in HIV-1-associated dementia (HAD)
remains unknown. To ascertain the role that cellular and viral macrophage products play in …

The pathogenesis of central nervous system disease during human immunodeficiency virus
type 1 (HIV-1) infection revolves around productive viral infection of brain macrophages and …

We examined cytokine‐mediated neuronal death in neuron‐astrocyte cultures from second
trimester human fetal cerebrum. In these cultures, high‐output inducible nitric oxide …

Human immunodeficiency virus type 1 (HIV) infection of the central nervous system is
characterized by neuronal loss in discrete areas of the central nervous system. We have …

Human immunodeficiency virus type 1 (HIV-1) infection of the developing central nervous
system results in a dementing process in children, termed HIV-1-associated …

Human immunodeficiency virus type 1 (HIV-1) infection is known to cause neuronal injury
and dementia in a significant proportion of patients. However, the mechanism by which HIV …