Glycomics aims to identify the structure and function of the glycome, the complete set of
oligosaccharides (glycans), produced in a given cell or organism, as well as to identify …

Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …

Despite the worldwide success of vaccination, newborns remain vulnerable to infections.
While neonatal vaccination has been hampered by maternal antibody-mediated dampening …

Metabolic alterations precede cardiometabolic disease onset. Here we present ceramide-
and dihydroceramide-profiling data from a nested case-cohort (type 2 diabetes [T2D, n …

Glycosylation is a topic of intense current interest in the development of biopharmaceuticals
because it is related to drug safety and efficacy. This work describes results of an …

Glycans are fundamental cellular building blocks, involved in many organismal functions.
Advances in glycomics are elucidating the essential roles of glycans. Still, it remains …

Background Acute respiratory distress syndrome (ARDS), a life-threatening condition
characterized by hypoxemia and poor lung compliance, is associated with high mortality …

N-glycosylation is a frequent modification of proteins, essential for all domains of life. N-
glycan biosynthesis is a dynamic, complex, non-templated process, wherein specific …

Abstract Gaussian Graphical Models (GGMs) are tools to infer dependencies between
biological variables. Popular applications are the reconstruction of gene, protein, and …

Immunoglobulin G (IgG), a glycoprotein secreted by plasma B-cells, plays a major role in the
human adaptive immune response and are associated with a wide range of diseases …