Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Hypertension is a major risk factor for many common chronic diseases, such as heart failure,
myocardial infarction, stroke, vascular dementia, and chronic kidney disease …

The cushioning function of large arteries encompasses distension during systole and recoil
during diastole which transforms pulsatile flow into a steady flow in the microcirculation …

Long non-coding RNAs (lncRNAs) are emerging regulators of pathophysiological processes
including atherosclerosis. Using RNA-seq profiling of the intima of lesions, here we identify a …

Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a
growing number of researchers have focused on the identification of target genes of …

Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …

In recent year, increasing evidence suggests that noncoding RNAs play important roles in
the regulation of tissue homeostasis and pathophysiological conditions. Besides small …

Recent studies suggest that the majority of the human genome is transcribed, but only about
2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a …

Vascular smooth muscle cells (VSMCs) are involved in phenotypic switching in
atherosclerosis. This switching is characterized by VSMC dedifferentiation, migration, and …

Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …