More than 40% of patients with late-stage colorectal cancer (CRC) develop liver metastasis
(LM). Which immune cells play important roles in CRC-LM and contribute to the difference …

Colorectal cancers have become the second leading cause of cancer-related deaths. In
particular, acquired chemoresistance and metastatic lesions occurring in colorectal cancer …

Background Given the differences in embryonic origin, vascular and nervous supplies,
microbiotic burden, and main physiological functions of left and right colons, tumor location …

There are well demonstrated differences in tumor cell metabolism between right sided
(RCC) and left sided (LCC) colon cancer, which could underlie the robust differences …

Colorectal carcinoma (CRC) is the second leading cause of cancer mortality worldwide.
CRC is stratified into two major groups: microsatellite stable (MSS) and microsatellite …

Purpose This study aimed to investigate the risk and prognostic factors of lymph node
metastasis (LNM) in early-onset colorectal cancer (EO-CRC) and to develop nomograms for …

Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

Complete mesocolic excision (CME) is a new concept of right hemicolectomy for colon
cancer (CC) set up to improve oncological outcomes and based on three main points …

This study explored the roles of activins and follistatin in colorectal cancers. Paired
malignant and normal colonic tissues were collected from archived paraffin-embedded (n …

Cancers arising from different regions of the colorectum are clinically and molecularly
distinct. 1-5 Right-sided tumors, which include those of the cecum, the ascending colon, and …