Obesity, a major risk factor for the development of diabetes mellitus, cardiovascular diseases
and certain types of cancer, arises from a chronic positive energy balance that is often due to …

Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …

Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone.
Considerable evidence implicates ghrelin in mealtime hunger and meal initiation …

Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …

Ghrelin, an endogenous brain–gut peptide, is secreted in large quantities, mainly from the
stomach, in humans and rodents. It can perform the biological function of activating the …

The growth hormone (GH) secretagogue receptor (GHSR) was cloned as the target of a
family of synthetic molecules endowed with GH release properties. As shown recently …

Immune and neuroendocrine systems have bidirectional communications. Growth hormone
(GH) and an orexigenic hormone ghrelin are expressed in various immune cells such as T …

Living organisms represent, in essence, dynamic interactions of high complexity between
membrane‐separated compartments that cannot exist on their own, but reach behaviour in …

Ghrelin is a multifaceted regulator of metabolism. Ghrelin regulates energy balance in the
short term via induction of appetite and in the long term via increased body weight and …

Ghrelin, identified as an endogenous ligand for the growth hormone secretagogue receptor,
functions as a somatotrophic and orexigenic signal from the stomach. Ghrelin has a unique …