Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …
numerous biotechnological applications. The NP discovery process is expensive and time …
Recent applications of high resolution mass spectrometry for the characterization of plant natural products
G Alvarez-Rivera, D Ballesteros-Vivas… - TrAC Trends in …, 2019 - Elsevier
Recently, the high analytical power provided by the new HRMS instruments (working in the
MS or MS/MS mode, stand alone or hyphenated with separation techniques) is making more …
MS or MS/MS mode, stand alone or hyphenated with separation techniques) is making more …
A review of the antimalarial, antitrypanosomal, and antileishmanial activities of natural compounds isolated from Nigerian flora
The West African country Nigeria features highly diverse vegetation and climatic conditions
that range from rain forest bordering the Atlantic Ocean in the South to the Desert (Sahara) …
that range from rain forest bordering the Atlantic Ocean in the South to the Desert (Sahara) …
Low and high resolution gas chromatography-mass spectrometry for untargeted metabolomics: A tutorial
F Rey-Stolle, D Dudzik, C Gonzalez-Riano… - Analytica Chimica …, 2022 - Elsevier
GC-MS for untargeted metabolomics is a well-established technique. Small molecules and
molecules made volatile by derivatization can be measured and those compounds are key …
molecules made volatile by derivatization can be measured and those compounds are key …
Expanding urinary metabolite annotation through integrated mass spectral similarity networking
The urine metabolome constitutes a rich source of functional information reflecting
physiological states that are influenced by distinct conditions and biological stresses, such …
physiological states that are influenced by distinct conditions and biological stresses, such …
[HTML][HTML] Metabolômica de plantas: métodos e desafios
Metabolomics has played a central role in various areas of plant sciences, offering new
perspectives for the advancement of agriculture, drug discovery, chemical ecology and …
perspectives for the advancement of agriculture, drug discovery, chemical ecology and …
Dereplication of flavonoid glycoconjugates from Adenocalymma imperatoris-maximilianii by untargeted tandem mass spectrometry-based molecular networking
GG de Oliveira, FC Neto, DP Demarque… - Planta …, 2017 - thieme-connect.com
The interpretation of large datasets acquired using high performance liquid chromatography
coupled with tandem mass spectrometry represents one of the major challenges in natural …
coupled with tandem mass spectrometry represents one of the major challenges in natural …
[HTML][HTML] Analysis of chemical deposits on tooth enamel exposed to total particulate matter from cigarette smoke and tobacco heating system 2.2 aerosol by novel GC …
A Haiduc, F Zanetti, X Zhao, WK Schlage… - … of Chromatography B, 2020 - Elsevier
Tobacco smoking contributes to tooth discoloration. Pigmented compounds in the smoke
generated by combustion of tobacco can cause discoloration of dental hard tissues …
generated by combustion of tobacco can cause discoloration of dental hard tissues …
Combination of GC-MS Molecular Networking and Larvicidal Effect against Aedes aegypti for the Discovery of Bioactive Substances in Commercial Essential Oils
AC Pilon, M Del Grande, MRS Silvério, RR Silva… - Molecules, 2022 - mdpi.com
Dengue is a neglected disease, present mainly in tropical countries, with more than 5.2
million cases reported in 2019. Vector control remains the most effective protective measure …
million cases reported in 2019. Vector control remains the most effective protective measure …
Discovery of antimalarial drugs from streptomycetes metabolites using a metabolomic approach
SJ Ahmad, MBH Abdul Rahim… - Journal of tropical …, 2017 - Wiley Online Library
Natural products continue to play an important role as a source of biologically active
substances for the development of new drug. Streptomyces, Gram‐positive bacteria which …
substances for the development of new drug. Streptomyces, Gram‐positive bacteria which …