Mast cell tumors (MCTs) are hematopoietic neoplasms composed of mast cells. It is highly
common in dogs and is extremely important in the veterinary oncology field. It represents the …

Mast cell tumor (MCT) or mastocytoma is one of the most frequent malignant cutaneous
tumors in the dog, and the second most frequent in the cat. Several mast cell tumor …

The use of chemical elixirs for the treatment of cancer can be traced through the medicinal
customs and practices of a number of cultures. 1 The modern use of pharmacologic agents …

The purpose of this study was to compare a maintenance‐free chemotherapy protocol
based on CHOP (H from hydroxydaunorubicin= doxorubicin, O from Oncovin®= vincristine) …

Forty‐one dogs with mast cell tumors (MCTs) were treated with oral prednisone and
injectable vinblastine (VBL), both in the adjuvant setting (23 dogs) and in dogs with gross …

To investigate the mechanism of vincristine-induced pain in humans undergoing
chemotherapy we have established a model of vincristine-induced hyperalgesia in rat …

The medical records of 61 dogs with MCT at high risk for metastasis that were treated with
prednisone and VBL following excision+/–radiation therapy were reviewed, and median …

The purpose of this study was to evaluate the efficacy and toxicity of an intensified dose
protocol with no maintenance phase for the treatment of canine lymphoma. Forty‐nine dogs …

The body's immune system is essential for protecting it from a variety of pathogens and other
external insults. It is through the complex interactions between the cells and mediators of …

Chemotherapeutic agents can be used to increase both the length and the quality of the
lives of patients with a wide variety of neoplastic diseases. The therapeutic index for many of …