This review describes the role of bone cells and their surrounding matrix in maintaining
bone strength through the process of bone remodeling. Subsequently, this work focusses on …

Teeth move through alveolar bone, whether through the normal process of tooth eruption or
by strains generated by orthodontic appliances. Both eruption and orthodontics accomplish …

Bone marrow is a viscous tissue that resides in the confines of bones and houses the vitally
important pluripotent stem cells. Due to its confinement by bones, the marrow has a unique …

Bone tissue engineering aims to generate clinically applicable bone graft substitutes in an
effort to ease the demands and reduce the potential risks associated with traditional …

In recent years, our scientific interest in spaceflight has grown exponentially and resulted in
a thriving area of research, with hundreds of astronauts spending months of their time in …

The strong correlation between a bone's architectural properties and the mechanical forces
that it experiences has long been attributed to the existence of a cell that not only detects …

Osteoblasts regulate the recruitment and activity of osteoclasts through expression of
RANKL and osteoprotegerin (OPG). To determine whether expression of RANKL and OPG …

Ex vivo engineering of autologous bone tissue as an alternative to bone grafting is a major
clinical need. In the present study, we evaluated the effect of 3‐D dynamic spinner flask …

Stromal/osteoblastic cell expression of RANKL and M‐CSF regulates osteoclastogenesis.
We show that aging is accompanied by increased RANKL and M‐CSF expression …

Bone marrow stromal cells (BMSCs) are multipotent progenitor cells with a capacity to form
bone tissue in vivo, and to differentiate into the osteoblastic lineage in vitro. Drawing on …