Survivin beyond physiology: orchestration of multistep carcinogenesis and therapeutic potentials

KC Athanasoula, H Gogas, K Polonifi, AG Vaiopoulos… - Cancer letters, 2014 - Elsevier
Survivin, a member of the inhibitor of apoptosis protein family, has been associated with
protection from cell apoptosis and regulation of mitosis. Survivin exhibits low to undetectable …

Survivin splice variants and their diagnostic significance

NK Sah, C Seniya - Tumor biology, 2015 - Springer
Survivin plays a crucial role in cell division particularly during the development of the fetus,
in the onset and progression of most tumors and is found expressed in a few terminally …

AS1411 aptamer-decorated cisplatin-loaded poly(lactic-co-glycolic acid) Nanoparticles for Targeted Therapy of miR-21-inhibited Ovarian Cancer Cells

S Vandghanooni, M Eskandani, J Barar, Y Omidi - Nanomedicine, 2018 - Taylor & Francis
Aim: The overexpression of miRNA-21 correlates with the cisplatin (CIS) resistance in the
ovarian cancers. Methods: AS1411 antinucleolin aptamer-decorated PEGylated poly (lactic …

Preparation, physicochemical characterization, and anti-proliferative properties of Lawsone-loaded solid lipid nanoparticles

F Rasouliyan, M Eskandani, M Jaymand… - Chemistry and physics …, 2021 - Elsevier
Lawsone (LWS) is a naphthoquinone-type dye with potential antitumor activity. LWS is used
in cosmetics for coloring hair, skin, and nails. In this study, solid lipid nanoparticles (SLNs) …

Preparation, characterization and anti-proliferative effects of sclareol-loaded solid lipid nanoparticles on A549 human lung epithelial cancer cells

H Hamishehkar, MB Bahadori, S Vandghanooni… - Journal of Drug Delivery …, 2018 - Elsevier
Here, sclareol-loaded solid lipid nanoparticles (sclareol-SLNs) was formulated and tested
for potential geno-cytotoxicity upon A549 lung cancer cells. Sclareol-SLNs was formulated …

Anticancer properties of curcumin-treated Lactobacillus plantarum against the HT-29 colorectal adenocarcinoma cells

F Gholipour, M Amini, B Baradaran, A Mokhtarzadeh… - Scientific Reports, 2023 - nature.com
Probiotic bacteria with functions of importance to the health and well-being of the host
exhibit various medicinal properties including anti-proliferative properties against cancer …

Antisense LNA-loaded nanoparticles of star-shaped glucose-core PCL-PEG copolymer for enhanced inhibition of oncomiR-214 and nucleolin-mediated therapy of …

S Vandghanooni, M Eskandani, J Barar… - International journal of …, 2020 - Elsevier
We aimed to inhibit overexpressed oncomiR-214 in cisplatin (CIS)-resistant ovarian cancer
(OC) and perform targeted therapy of sensitized cells using a novel polymeric drug delivery …

Clinico-pathologic relevance of Survivin splice variant expression in cancer

R de Necochea-Campion, CS Chen, S Mirshahidi… - Cancer letters, 2013 - Elsevier
Survivin is a member of the inhibitor of apoptosis (IAP) family and has multifunctional
properties that include aspects of proliferation, invasion and cell survival control. Survivin is …

Galbanic acid inhibits HIF-1α expression via EGFR/HIF-1α pathway in cancer cells

M Eskandani, J Abdolalizadeh, H Hamishehkar… - Fitoterapia, 2015 - Elsevier
Abstract Hypoxia Inducible Factor-1 plays a key transcriptional role in the adaptation of
hypoxic solid tumors to low oxygen environment. Here, we aimed to investigate galbanic …

miR-21 induces chemoresistance in ovarian cancer cells via mediating the expression and interaction of CD44v6 and P-gp

Y Wang, G Chen, F Dai, L Zhang, M Yuan… - OncoTargets and …, 2021 - Taylor & Francis
Background Ovarian cancer (OC), a representative female reproductive system tumor, is one
of the most malignant tumors in female. The most important reason for its poor prognosis is …