The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

The last decades have seen a major gain in understanding the action of cannabinoids and
the endocannabinoid system in reward processing and the development of addictive …

Alcohol consumption is an integral part of daily life in many societies. The benefits
associated with the production, sale, and use of alcoholic beverages come at an enormous …

Despite the generally held view that alcohol is an unspecific pharmacological agent, recent
molecular pharmacology studies demonstrated that alcohol has only a few known primary …

Recent studies have shown that the endocannabinoid system is involved in the common
neurobiological mechanism underlying drug addiction. This system participates in the …

Alcohol use disorder (AUD) encompasses the dysregulation of multiple brain circuits
involved in executive function leading to excessive consumption of alcohol, despite negative …

Alcoholism is a major public health problem and resembles, in many ways, other chronic
relapsing medical conditions. At least 2 separate dimensions of its symptomatology offer …

Addiction is a devastating disorder that affects 15.3 million people worldwide. While
prevalent, few effective treatments exist. Orexin receptors have been proposed as a potential …

The past decade has seen an expansion of research and knowledge on pharmacotherapy
for the treatment of alcohol dependence. The Food and Drug Administration (FDA)-approved …

Food, drugs and brain stimulation can serve as strong rewarding stimuli and are all believed
to activate common brain circuits that evolved in mammals to favour fitness and survival. For …