DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

[HTML][HTML] Nuclease resistance of DNA nanostructures

AR Chandrasekaran - Nature Reviews Chemistry, 2021 - nature.com
DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …

DNA nanotechnology-enabled drug delivery systems

Q Hu, H Li, L Wang, H Gu, C Fan - Chemical reviews, 2018 - ACS Publications
Over the past decade, we have seen rapid advances in applying nanotechnology in
biomedical areas including bioimaging, biodetection, and drug delivery. As an emerging …

[HTML][HTML] Chitosan hydrogel/3D-printed poly (ε‐caprolactone) hybrid scaffold containing synovial mesenchymal stem cells for cartilage regeneration based on …

P Li, L Fu, Z Liao, Y Peng, C Ning, C Gao, D Zhang… - Biomaterials, 2021 - Elsevier
Articular cartilage (AC) injury repair has always been a difficult problem for clinicians and
researchers. Recently, a promising therapy based on mesenchymal stem cells (MSCs) has …

Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

[HTML][HTML] Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation

N Ponnuswamy, MMC Bastings, B Nathwani… - Nature …, 2017 - nature.com
DNA nanostructures have evoked great interest as potential therapeutics and diagnostics
due to ease and robustness of programming their shapes, site-specific functionalizations …

Challenges and perspectives of DNA nanostructures in biomedicine

A Keller, V Linko - Angewandte Chemie International Edition, 2020 - Wiley Online Library
DNA nanotechnology holds substantial promise for future biomedical engineering and the
development of novel therapies and diagnostic assays. The subnanometer‐level …

DNA nanotechnology from the test tube to the cell

YJ Chen, B Groves, RA Muscat, G Seelig - Nature nanotechnology, 2015 - nature.com
Abstract The programmability of Watson–Crick base pairing, combined with a decrease in
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …

A megatrend challenging analytical chemistry: biosensor and chemosensor concepts ready for the internet of things

M Mayer, AJ Baeumner - Chemical reviews, 2019 - ACS Publications
The Internet of Things (IoT) is a megatrend that cuts across all scientific and engineering
disciplines and establishes an integrating technical evolution to improve production …

DNA nanostructures: current challenges and opportunities for cellular delivery

A Lacroix, HF Sleiman - ACS nano, 2021 - ACS Publications
DNA nanotechnology has produced a wide range of self-assembled structures, offering
unmatched possibilities in terms of structural design. Because of their programmable …