Simple Summary Breast cancer continues to be the number one cause of cancer mortality
among women. Because breast cancer is a heterogenous disease there is a need for a …

Emerging evidence suggests that genetically highly specific triple-negative breast cancer
(TNBC) possesses a relatively uniform transcriptional program that is abnormally dependent …

Abstract 27 novel 5-(4-hydroxyphenyl)-3H-1, 2-dithiole-3-thione derivatives of brefeldin A
were designed and synthesized to make them more conducive to the cancer treatment. The …

Background In this work, we represent synthesis, in silico analysis and biological activity of
1, 4 diazepine linked piperidine derivatives (6a–6o). All the derivatives were screened for …

Breast cancer is one of the leading causes of death among women globally, making its
diagnosis and treatment challenging. The use of nanotechnology for cancer diagnosis and …

Polyphyllin D (PD), one of the important steroid saponins in traditional medicinal herb Paris
polyphylla, has been demonstrated to have anticancer activity both in vitro and in vivo …

Background Previous investigations showed that jojoba oil exhibited a protective effect
against hepatotoxicity caused by different toxicants, however, to the best of our knowledge …

Despite the major progress in treating breast cancer, recurrence remains a problem and
types such as triple-negative breast cancer still lack targeted medicine. The orphan Sigma …