Among heterocyclic compounds, quinoline scaffold has become an important construction
motif for the development of new drugs. Quinoline and its derivatives possess many types of …

Cancer is the second leading cause of death worldwide. There is always a huge demand for
novel anticancer drugs and diverse new natural or synthetic compounds are developed …

New drugs with new mechanisms of action are urgently required to tackle the global
tuberculosis epidemic. Following the FDA-approval of the ATP synthase inhibitor …

This paper reports the synthesis, structure characterization, and anticancer properties of 13
organometallic Ru (II)–arene complexes:[Ru (η6-p-cymene) Cl-(L1)](1),[Ru (η6-p-cymene) …

Cancer is one of the most difficult diseases and causes of death for many decades. Many
pieces of research are continuously going on to get a solution for cancer. Quinoline and …

Causing approximately 10 million incident cases and 1.3–1.5 million deaths every year,
Mycobacterium tuberculosis remains a global health problem. The risk is further …

Literature conclusively shows that one of the quinolinequinone analogs (6-anilino-5, 8-
quinolinequinone), referred to as LY83583 hereafter, an inhibitor of guanylyl cyclase, was …

Quinone-based small molecules are the promising structures for antiproliferative drug
design and can induce apoptosis in cancer cells. Among them, one of the …

Abstract Indoleamine 2, 3-dioxygenase 1 (IDO1) mediated kynurenine pathway of
tryptophan degradation is identified as an appealing and novel target in immunotherapy for …

Abstract Betulin-1, 4-quinone hybrids were obtain by connecting two active structures with a
linker. This strategy allows for obtaining compounds showing a high biological activity and …