Lentiviruses induce a wide variety of pathologies in different animal species. A common
feature of the replicative cycle of these viruses is their ability to target non-dividing cells, a …

Transfer RNA (tRNA) molecules are sumptuously decorated with evolutionary conserved
post-transcriptional nucleoside modifications that are essential for structural stability and …

The human immunodeficiency virus (HIV) produces the pathologic basis of acquired
immunodeficiency syndrome (AIDS). An increase in the viral load in the body leads to a …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

Post-mortem examination is a key step in the diagnostic process of infectious diseases in
sheep and goats. Diagnostic pathology deals with identification and study of lesions, at the …

This paper offers an overview of important veterinary viral diseases of mammals stemming
from aberrant immune response. Diseases reviewed comprise those due to lentiviruses of …

Chronic interstitial pneumonia (CIP) is a main pathology of sheep infected with small
ruminant lentivirus (SRLV). Caprine arthritis-encephalitis (CAE) is caused by the same …

Diagnosis of feline immunodeficiency virus (FIV) infection by polymerase chain reaction
(PCR) has recently become available, but little is known about the performance of this …

Electroporation serves as a promising non-viral gene delivery approach, while its current
configuration carries several drawbacks associated with high-voltage electrical pulses and …

Lentiviral vectors (LV) are efficient vehicles for gene transfer in mammalian cells due to their
capacity to stably express a gene of interest in non-dividing and dividing cells. Their use has …