Sex significantly impacts the function of major depression–linked variants in vivo
Background Genome-wide association studies have discovered blocks of common variants—
likely transcriptional-regulatory—associated with major depressive disorder (MDD), though …
likely transcriptional-regulatory—associated with major depressive disorder (MDD), though …
Acetylated chromatin domains link chromosomal organization to cell-and circuit-level dysfunction in schizophrenia and bipolar disorder
To explore modular organization of chromosomes in schizophrenia (SCZ) and bipolar
disorder (BD), we applied 'population-scale'correlational structuring of 739 histone H3-lysine …
disorder (BD), we applied 'population-scale'correlational structuring of 739 histone H3-lysine …