Rethinking Nano‐TiO2 Safety: Overview of Toxic Effects in Humans and Aquatic Animals

Z Luo, Z Li, Z Xie, IM Sokolova, L Song… - Small, 2020 - Wiley Online Library
Titanium dioxide nanoparticles (nano‐TiO2) are widely used in consumer products, raising
environmental and health concerns. An overview of the toxic effects of nano‐TiO2 on human …

Murine liver damage caused by exposure to nano-titanium dioxide

J Hong, YQ Zhang - Nanotechnology, 2016 - iopscience.iop.org
Due to its unique physiochemical properties, nano-titanium dioxide (nano-TiO 2) is widely
used in all aspects of people's daily lives, bringing it into increasing contact with humans …

Physiological effect of anatase TiO2 nanoparticles on Lemna minor

G Song, Y Gao, H Wu, W Hou… - Environmental …, 2012 - Wiley Online Library
Manufactured metal oxide nanoparticles (NPs) are being used on a large scale, and these
particles will inevitably reach a body of water through wastewater and urban runoff. The …

Hepatotoxicity and the role of the gut-liver axis in rats after oral administration of titanium dioxide nanoparticles

Z Chen, D Zhou, S Han, S Zhou, G Jia - Particle and fibre toxicology, 2019 - Springer
Background Due to its excellent physicochemical properties and wide applications in
consumer goods, titanium dioxide nanoparticles (TiO 2 NPs) have been increasingly …

Cytotoxicity, DNA damage, and apoptosis induced by titanium dioxide nanoparticles in human non-small cell lung cancer A549 cells

Y Wang, H Cui, J Zhou, F Li, J Wang, M Chen… - … Science and Pollution …, 2015 - Springer
Concerns about the risk of titanium dioxide nanoparticles (TiO 2 NPs) to human health and
environment are gradually increasing due to their wide range of applications. In this study …

NLRP3 inflammasome, oxidative stress, and apoptosis induced in the intestine and liver of rats treated with titanium dioxide nanoparticles: in vivo and in vitro study

E Abbasi-Oshaghi, F Mirzaei… - International journal of …, 2019 - Taylor & Francis
Purpose This study evaluated the effects of titanium dioxide nanoparticles (TiO2 NPs) on
liver and intestine of normal rats. Methods Male rats were divided into four groups as follows …

Grape Seed Proanthocyanidin Extract Mitigates Titanium Dioxide Nanoparticle (TiO2-NPs)–Induced Hepatotoxicity Through TLR-4/NF-κB Signaling Pathway

ET Mohammed, GM Safwat - Biological trace element research, 2020 - Springer
With the progress of nanotechnology, the adverse effects of nanoscale materials are
receiving much attention. Inhibition of toll-like receptor 4 (TLR-4)/nuclear factor kappa B (NF …

Eugenol attenuates TiO2 nanoparticles-induced oxidative damage, biochemical toxicity and DNA damage in Wistar rats: an in vivo study

MR Wani, N Maheshwari, G Shadab - Environmental Science and …, 2021 - Springer
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) are widely used in food, edible dyes,
and other commercial products. Human exposure to TiO 2 NPs has raised concerns …

Cytotoxic and genotoxic effects of titanium dioxide nanoparticles in testicular cells of male wistar rat

R Meena, K Kajal - Applied Biochemistry and Biotechnology, 2015 - Springer
Serious concerns have been expressed about potential risks of engineered nanoparticles.
Regulatory health risk assessment of such particles has become mandatory for the safe use …

Titanium dioxide nanoparticles trigger loss of function and perturbation of mitochondrial dynamics in primary hepatocytes

V Natarajan, CL Wilson, SL Hayward, S Kidambi - PloS one, 2015 - journals.plos.org
Titanium dioxide (TiO2) nanoparticles are one of the most highly manufactured and
employed nanomaterials in the world with applications in copious industrial and consumer …