Physical principles of nanoparticle cellular endocytosis
This review article focuses on the physiochemical mechanisms underlying nanoparticle
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …
Biomechanics and biorheology of red blood cells in sickle cell anemia
Sickle cell anemia (SCA) is an inherited blood disorder that causes painful crises due to
vaso-occlusion of small blood vessels. The primary cause of the clinical phenotype of SCA is …
vaso-occlusion of small blood vessels. The primary cause of the clinical phenotype of SCA is …
Continuum-and particle-based modeling of shapes and dynamics of red blood cells in health and disease
We review recent advances in multiscale modeling of the mechanics of healthy and
diseased red blood cells (RBCs), and blood flow in the microcirculation. We cover the …
diseased red blood cells (RBCs), and blood flow in the microcirculation. We cover the …
Computational biomechanics of human red blood cells in hematological disorders
We review recent advances in multiscale modeling of the biomechanical characteristics of
red blood cells (RBCs) in hematological diseases, and their relevance to the structure and …
red blood cells (RBCs) in hematological diseases, and their relevance to the structure and …
Circulating cell clusters aggravate the hemorheological abnormalities in COVID-19
Microthrombi and circulating cell clusters are common microscopic findings in patients with
coronavirus disease 2019 (COVID-19) at different stages in the disease course, implying …
coronavirus disease 2019 (COVID-19) at different stages in the disease course, implying …
A computational study of fibrinogen-induced alteration in microvascular blood flow in COVID-19
Patients infected with COVID-19 may experience significant and long-lasting changes in the
mechanical and rheological properties of their blood cells, leading to microvascular …
mechanical and rheological properties of their blood cells, leading to microvascular …
Effect of chain chirality on the self-assembly of sickle hemoglobin
X Li, B Caswell, GE Karniadakis - Biophysical journal, 2012 - cell.com
We present simulation results on the self-assembly behavior of sickle hemoglobin (HbS). A
coarse-grained HbS model, which contains hydrophilic and hydrophobic particles explicitly …
coarse-grained HbS model, which contains hydrophilic and hydrophobic particles explicitly …
Synergistic integration of laboratory and numerical approaches in studies of the biomechanics of diseased red blood cells
In red blood cell (RBC) disorders, such as sickle cell disease, hereditary spherocytosis, and
diabetes, alterations to the size and shape of RBCs due to either mutations of RBC proteins …
diabetes, alterations to the size and shape of RBCs due to either mutations of RBC proteins …
Dynamic and rheological properties of soft biological cell suspensions
A Yazdani, X Li, GE Karniadakis - Rheologica acta, 2016 - Springer
Quantifying dynamic and rheological properties of suspensions of soft biological particles
such as vesicles, capsules, and red blood cells (RBCs) is fundamentally important in …
such as vesicles, capsules, and red blood cells (RBCs) is fundamentally important in …
Closing the gap between modeling and experiments in the self-assembly of biomolecules at interfaces and in solution
Molecular self-assembly is a powerful tool in materials design, wherein noncovalent
interactions like electrostatic, hydrophobic, hydrogen bonding, and van der Waals can be …
interactions like electrostatic, hydrophobic, hydrogen bonding, and van der Waals can be …