Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

The association properties of poly (ethylene oxide)-block-poly (propyleneoxide)-block-poly
(ethylene oxide)(PEO PPO PEO) copolymers (commercially available as Poloxamers …

The critical micellization temperature (cmt) and critical micellization concentration (cmc)
values of 12 Plutonic polyethylene oxide)-poly (propylene oxide)-poly (ethylene oxide)(PEO …

Surfactants are used to stabilize biologics. Particularly, polysorbates (Tween® 20 and
Tween® 80) dominate the group of surfactants in protein and especially antibody drug …

The cell therapy industry is a fast-growing industry targeted toward a myriad of clinical
indications. As the cell therapy industry matures and clinical trials hit their pivotal Phase 3 …

Background To simplify clinical scale lymphocyte expansions, we investigated the use of the
WAVE®, a closed system bioreactor that utilizes active perfusion to generate high cell …

High density cell culture systems offer the advantage of production of bio-pharmaceuticals in
compact bioreactors with high volumetric production rates; however, these systems are …

Novel diagnostic and testing methodologies, the production of recombinant DNA-derived
proteins and the emerging area of advanced gene or somatic therapy and transplantations …

Burn injuries, the most common and destructive forms of wounds, are generally
accompanied with life-threatening infections, inflammation, reduced angiogenesis …

The structure of (ethylene oxide) 26 (propylene oxide) 40 (ethylene oxide) 26 Pluronic P85
block copolymer micelles in the unimer-to-micelle transition region was studied using small …