[HTML][HTML] Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology

A Yokoi, T Ochiya - Seminars in cancer biology, 2021 - Elsevier
Extracellular vesicles (EVs) such as exosomes are released by all living cells and contain
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …

[HTML][HTML] Exosomes as drug delivery systems: endogenous nanovehicles for treatment of systemic lupus erythematosus

A Ortega, O Martinez-Arroyo, MJ Forner, R Cortes - Pharmaceutics, 2021 - mdpi.com
Exosomes, nanometer-sized lipid-bilayer-enclosed extracellular vesicles (EVs), have
attracted increasing attention due to their inherent ability to shuttle proteins, lipids and genes …

Atorvastatin enhances the efficacy of immune checkpoint therapy and suppresses the cellular and extracellular vesicle PD-L1

EJ Choe, CH Lee, JH Bae, JM Park, SS Park, MC Baek - Pharmaceutics, 2022 - mdpi.com
According to clinical studies, statins improve the efficacy of programmed death-
1/programmed death-ligand 1 (PD-1/PD-L1) blockade therapy for breast cancer; however …

Exosomes derived from myeloid-derived suppressor cells facilitate castration-resistant prostate cancer progression via S100A9/circMID1/miR-506-3p/MID1

F Gao, Q Xu, Z Tang, N Zhang, Y Huang, Z Li… - Journal of translational …, 2022 - Springer
Background Castration-resistant prostate cancer (CRPC) is a major cause of recurrence and
mortality among prostate cancer (PCa) patients. Myeloid-derived suppressor cells (MDSCs) …

Therapeutic and diagnostic potential of exosomes as drug delivery systems in brain cancer

DI Avgoulas, KS Tasioulis, RM Papi, AA Pantazaki - Pharmaceutics, 2023 - mdpi.com
Cancer is designated as one of the principal causes of mortality universally. Among different
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …

Exosomal miRNAs as potential diagnostic biomarkers in Alzheimer's disease

I Manna, S De Benedittis, A Quattrone, D Maisano… - Pharmaceuticals, 2020 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative disease, is linked to a variety of internal and
external factors present from the early stages of the disease. There are several risk factors …

TKI-resistant renal cancer secretes low-level exosomal miR-549a to induce vascular permeability and angiogenesis to promote tumor metastasis

Z Xuan, C Chen, W Tang, S Ye, J Zheng… - Frontiers in cell and …, 2021 - frontiersin.org
Tyrosine kinase inhibitors (TKI)-resistant renal cancer is highly susceptible to metastasis,
and enhanced vascular permeability promotes the process of metastasis. To evaluate the …

Diagnostic role of extracellular vesicles in cancer: a comprehensive systematic review and meta-analysis

SY Liu, Y Liao, H Hosseinifard, S Imani… - Frontiers in Cell and …, 2021 - frontiersin.org
Background: Cancer-derived extracellular vesicles (EVs) are regarded to have significant
function in most steps during cancer progression. This meta-analysis aims to investigate the …

The role of liquid biopsy in hepatocellular carcinoma prognostication

I Labgaa, A Villanueva, O Dormond, N Demartines… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is one of the deadliest cancer. Clinical
guidelines for the management of HCC endorse algorithms deriving from clinical variables …

microRNAs in female infertility: An overview

S Bahmyari, Z Jamali, SH Khatami… - Cell Biochemistry …, 2021 - Wiley Online Library
Infertility impacts a considerable number of women worldwide, and it affects different aspects
of family life and society. Although female infertility is known as a multifactorial disorder …