Mechanical ventilation applies physical stresses to the tissues of the lung and thus may give
rise to ventilator-induced lung injury (VILI), particular in patients with acute respiratory …

The development of acute ventilatory failure represents an inability of the respiratory control
system to maintain a level of respiratory motor output to cope with the metabolic demands of …

Secretion of pulmonary surfactant that maintains low surface tension within the lung is
primarily mediated by mechanical stretching of alveolar epithelial type II (AEII) cells. We …

Background Neurally adjusted ventilatory assist (NAVA) is a partial ventilatory support mode
where positive pressure is provided in relation to diaphragmatic electrical activity (EAdi) …

Introduction Mechanical ventilation (MV) of mice is increasingly required in experimental
studies, but the conditions that allow stable ventilation of mice over several hours have not …

This article is one of ten reviews selected from the Yearbook of Intensive Care and
Emergency Medicine 2010 (Springer Verlag) and co-published as a series in Critical Care …

Lung recruitment and derecruitment contribute significantly to variations in the elastance of
the respiratory system during mechanical ventilation. However, the decreases in elastance …

The accepted protocol to ventilate patients with acute lung injury is to use low tidal volume
(VT) in combination with recruitment maneuvers or positive end-expiratory pressure (PEEP) …

In patients with acute lung injury and acute respiratory distress syndrome, a protective
mechanical ventilation strategy characterized by low tidal volumes has been associated with …

Background Introducing mathematically derived variability (MVV) into the otherwise
monotonous conventional mechanical ventilation has been suggested to improve lung …