Recent developments in the field of oxa-Michael reactions
CF Nising, S Bräse - Chemical Society Reviews, 2012 - pubs.rsc.org
Oxa-Michael reactions, ie addition reactions of oxygen nucleophiles to conjugated systems,
have traditionally received much less attention from the scientific community compared to …
have traditionally received much less attention from the scientific community compared to …
A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues
This compendium focuses on functionalised sugar amino acids (SAAs) and their 3-to 6-
membered nitrogen heterocyclic and carbocyclic analogues. The main benefit of using SAAs …
membered nitrogen heterocyclic and carbocyclic analogues. The main benefit of using SAAs …
Total synthesis of pachastrissamine together with its 4-epi-congener via [3, 3]-sigmatropic rearrangements and antiproliferative/cytotoxic evaluation
M Martinková, E Mezeiová, M Fabišíková, J Gonda… - Carbohydrate …, 2015 - Elsevier
Synthesis of the HCl salts of two anhydrophytosphingosines, jaspine B (1) and its 4-epi-
congener 5 from easily available dimethyl l-tartrate and/or l-arabinose, is described. The key …
congener 5 from easily available dimethyl l-tartrate and/or l-arabinose, is described. The key …
Syntheses of sulfur and selenium analogues of pachastrissamine via double displacements of cyclic sulfate
H Jeon, H Bae, DJ Baek, YS Kwak, D Kim… - Organic & Biomolecular …, 2011 - pubs.rsc.org
Bioisosteric analogues of pachastrissamine that contain sulfur and selenium atoms
replacing the oxygen in the ring system, were efficiently prepared from a cyclic sulfate …
replacing the oxygen in the ring system, were efficiently prepared from a cyclic sulfate …
Synthesis of pachastrissamine (jaspine B) and its derivatives by the late-stage introduction of the C-2 alkyl side-chains using olefin cross metathesis
Y Yoshimitsu, J Miyagaki, S Oishi, N Fujii, H Ohno - Tetrahedron, 2013 - Elsevier
An improved divergent synthesis of the four diastereomers of pachastrissamine from
Garner's aldehyde has been reported. The common intermediate was synthesized by an …
Garner's aldehyde has been reported. The common intermediate was synthesized by an …
Total synthesis and the anticancer activity of (+)-spisulosine
M Fabišíková, M Martinková, S Hirková, J Gonda… - Carbohydrate …, 2016 - Elsevier
The total synthesis of the anticancer agent (+)-spisulosine has been accomplished. The
strategy involved a substrate-controlled aza-Claisen rearrangement to establish the erythro …
strategy involved a substrate-controlled aza-Claisen rearrangement to establish the erythro …
Marine cytotoxic jaspine B and its stereoisomers: Biological activity and syntheses
M Martinková, J Gonda - Carbohydrate Research, 2016 - Elsevier
Conformationally constrained sphingolipids such as anhydrophytosphingosines
represented by jaspine B (also known as pachastrissamine) and its stereoisomers have …
represented by jaspine B (also known as pachastrissamine) and its stereoisomers have …
Total synthesis of (−)-jaspine B and its 4-epi-analogue from d-xylose
M Martinkova, E Mezeiova, J Gonda, D Jackova… - Tetrahedron …, 2014 - Elsevier
The total synthesis of the HCl salts of (−)-jaspine B ent-1 and its 4-epi-congener ent-4 was
accomplished starting from the common template 13 derived from d-xylose. The cornerstone …
accomplished starting from the common template 13 derived from d-xylose. The cornerstone …
A common approach to the total synthesis of L-arabino-, L-ribo-C18-phytosphingosines, ent-2-epi-jaspine B and 3-epi-jaspine B from D-mannose
M Martinková, K Pomikalová, J Gonda, M Vilková - Tetrahedron, 2013 - Elsevier
A common strategy for the total syntheses of the protected l-arabino-and l-ribo-C 18-
phytosphingosine (8 and 9, respectively), HCl salts of ent-2-epi-jaspine B (ent-6) and 3-epi …
phytosphingosine (8 and 9, respectively), HCl salts of ent-2-epi-jaspine B (ent-6) and 3-epi …
Simple marine 1-deoxysphingoid bases: biological activity and syntheses
M Martinkova, J Gonda, D Jackova - Tetrahedron: Asymmetry, 2016 - Elsevier
Over the past decade, simple 1-deoxysphingoid bases with a saturated hydrocarbon side-
chain have attracted considerable attention from synthetic organic chemists because of their …
chain have attracted considerable attention from synthetic organic chemists because of their …