Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …

Acute respiratory distress syndrome (ARDS) is characterized by the severe inflammation
and destruction of the lung air–blood barrier, leading to irreversible and substantial …

Abstract Background Polymorphonuclear neutrophils (PMNs) play an important role in
sepsis-related acute lung injury (ALI). Accumulating evidence suggests PMN-derived …

Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly
correlated with a worse prognosis. Excessive neutrophil extracellular traps (NETs) are …

Hyperferritinemic syndrome, an overwhelming inflammatory condition, is characterized by
high ferritin levels, systemic inflammation and multi-organ dysfunction, but the pathogenic …

Neutrophils are the most abundant human white blood cell and constitute a first line of
defense in the innate immune response. Neutrophils are short-lived cells and thus the …

Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are
renowned for their propensity to expel decondensed chromatin embedded with inflammatory …

Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …

Neutrophils are the most abundant type of leukocytes in the blood, traditionally regarded as
the first immune responders to infections and inflammations. In the context of tumors …

A cytokine storm is an abnormal discharge of soluble mediators following an inappropriate
inflammatory response that leads to immunopathological events. Cytokine storms can occur …