Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species
C Paulussen, JE Hallsworth… - Microbial …, 2017 - Wiley Online Library
Fungi of the genus Aspergillus are widespread in the environment. Some Aspergillus
species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions …
species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions …
[HTML][HTML] Ser/Thr protein phosphatases in fungi: structure, regulation and function
Reversible phospho-dephosphorylation of proteins is a major mechanism for the control of
cellular functions. By large, Ser and Thr are the most frequently residues phosphorylated in …
cellular functions. By large, Ser and Thr are the most frequently residues phosphorylated in …
A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi
TF Dos Reis, PA De Castro, RW Bastos… - Nature …, 2023 - nature.com
Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal
drug resistance, novel strategies are urgently needed to combat life-threatening fungal …
drug resistance, novel strategies are urgently needed to combat life-threatening fungal …
Mitogen activated protein kinases SakAHOG1 and MpkC collaborate for Aspergillus fumigatus virulence
ACMO Bruder Nascimento, TF Dos Reis… - Molecular …, 2016 - Wiley Online Library
Here, we investigated which stress responses were influenced by the MpkC and SakA
mitogen‐activated protein kinases of the high‐osmolarity glycerol (HOG) pathway in the …
mitogen‐activated protein kinases of the high‐osmolarity glycerol (HOG) pathway in the …
The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance
NA Brown, GH Goldman - Journal of Microbiology, 2016 - Springer
Invasive aspergillosis has emerged as one of the most common life-threatening fungal
disease of humans. The emergence of antifungal resistant pathogens represents a current …
disease of humans. The emergence of antifungal resistant pathogens represents a current …
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
JH Jin, KT Lee, J Hong, D Lee, EH Jang, JY Kim… - Nature …, 2020 - nature.com
Phosphatases, together with kinases and transcription factors, are key components in
cellular signalling networks. Here, we present a systematic functional analysis of the …
cellular signalling networks. Here, we present a systematic functional analysis of the …
Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus
R Altwasser, C Baldin, J Weber, R Guthke… - PLoS …, 2015 - journals.plos.org
Mitogen activated protein kinases (MAPKs) are highly conserved in eukaryotic organisms. In
pathogenic fungi, their activities were assigned to different physiological functions including …
pathogenic fungi, their activities were assigned to different physiological functions including …
The cell wall integrity signaling pathway and its involvement in secondary metabolite production
V Valiante - Journal of Fungi, 2017 - mdpi.com
The fungal cell wall is the external and first layer that fungi use to interact with the
environment. Every stress signal, before being translated into an appropriate stress …
environment. Every stress signal, before being translated into an appropriate stress …
MAPK pathway‐related tyrosine phosphatases regulate development, secondary metabolism and pathogenicity in fungus Aspergillus flavus
G Yang, X Cao, G Ma, L Qin, Y Wu, J Lin… - Environmental …, 2020 - Wiley Online Library
Mitogen‐activated protein kinase (MAPK) cascades are highly conserved in eukaryotic cells
and are known to play crucial roles in the regulation of various cellular processes. However …
and are known to play crucial roles in the regulation of various cellular processes. However …
Metal-homeostasis in the pathobiology of the opportunistic human fungal pathogen Aspergillus fumigatus
M Blatzer, JP Latgé - Current opinion in microbiology, 2017 - Elsevier
Highlights•Aspergillus fumigatus requires metal ion uptake in the host environment.•Metal-
homeostatic circuits are complex and multifactorial.•Imbalances in metal homeostasis affect …
homeostatic circuits are complex and multifactorial.•Imbalances in metal homeostasis affect …