The risk of infections for multiple sclerosis and neuromyelitis optica spectrum disorder disease-modifying treatments: Eighth European Committee for Treatment and …

C Tur, AL Dubessy, S Otero-Romero… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Over the recent years, the treatment of multiple sclerosis (MS) and neuromyelitis optica
spectrum disorder (NMOSD) has evolved very rapidly and a large number of disease …

Advances in treatment of progressive multifocal leukoencephalopathy

R Bernard‐Valnet, IJ Koralnik… - Annals of …, 2021 - Wiley Online Library
Progressive multifocal encephalopathy (PML) is a severe demyelinating disease of the
central nervous system (CNS) caused by JC virus (JCV), which occurs in …

Adoptive transfer of JC virus‐specific T lymphocytes for the treatment of progressive multifocal leukoencephalopathy

G Berzero, S Basso, L Stoppini, A Palermo… - Annals of …, 2021 - Wiley Online Library
Objective Progressive multifocal leukoencephalopathy (PML) is still burdened by high
mortality in a subset of patients, such as those affected by hematological malignancies. The …

[HTML][HTML] Immunocompromised host section: Adoptive T-cell therapy for dsDNA viruses in allogeneic hematopoietic cell transplant recipients

CS Walti, C Stuehler, D Palianina… - Current Opinion in …, 2022 - journals.lww.com
Immunocompromised host section: Adoptive T-cell therapy for... : Current Opinion in
Infectious Diseases Immunocompromised host section: Adoptive T-cell therapy for dsDNA …

[HTML][HTML] Innovative therapeutic concepts of progressive multifocal leukoencephalopathy

N Möhn, L Grote-Levi, F Hopfner, B Eiz-Vesper… - Journal of …, 2022 - Springer
Progressive multifocal leukoencephalopathy (PML) is an opportunistic viral disease of the
brain—caused by human polyomavirus 2. It affects patients whose immune system is …

Allogeneic BK virus-specific T-cell treatment in 2 patients with progressive multifocal leukoencephalopathy

F Hopfner, N Möhn, B Eiz-Vesper… - Neurology …, 2021 - AAN Enterprises
Objective Progressive multifocal leukoencephalopathy (PML) is a devastating demyelinating
opportunistic infection of the brain caused by the ubiquitously distributed JC polyomavirus …

[HTML][HTML] Facilitating drug delivery in the central nervous system by opening the blood-cerebrospinal fluid barrier with a single low energy shockwave pulse

Y Kung, KY Chen, WH Liao, YH Hsu, CH Wu… - Fluids and Barriers of …, 2022 - Springer
Background The blood-cerebrospinal fluid (CSF) barrier (BCSFB) is critically important to the
pathophysiology of the central nervous system (CNS). However, this barrier prevents the …

[HTML][HTML] Off-the-shelf third-party virus-specific T cell therapy to treat JC polyomavirus infection in hematopoietic stem cell transplantation recipients

JD Rubinstein, S Jodele, D Heyenbruch… - … and cellular therapy, 2022 - Elsevier
Progressive multifocal leukoencephalopathy (PML) is a progressive and generally fatal
demyelinating neurologic disease that occurs in profoundly immunocompromised patients …

[HTML][HTML] Pathogen-specific T cells: targeting old enemies and new invaders in transplantation and beyond

A Papadopoulou, M Alvanou, G Karavalakis… - …, 2023 - journals.lww.com
Adoptive immunotherapy with virus-specific cytotoxic T cells (VSTs) has evolved over the
last three decades as a strategy to rapidly restore virus-specific immunity to prevent or treat …

[HTML][HTML] Rapid manufacturing of highly cytotoxic clinical-grade SARS-CoV-2-specific T cell products covering SARS-CoV-2 and its variants for adoptive T cell therapy

A Bonifacius, S Tischer-Zimmermann… - … in Bioengineering and …, 2022 - frontiersin.org
Objectives: Evaluation of the feasibility of SARS-CoV-2-specific T cell manufacturing for
adoptive T cell transfer in COVID-19 patients at risk to develop severe disease. Methods …