Hypercoagulable states in cardiovascular disease

MY Chan, F Andreotti, RC Becker - Circulation, 2008 - Am Heart Assoc
interactions, because monozygotic twins share 100% of their genes, whereas dizygotic twins
on average share only 50% of their genome. Genetic model fitting showed that gene coding …

Associations of coagulation factor V Leiden and prothrombin G20210A mutations with Budd–Chiari syndrome and portal vein thrombosis: a systematic review and …

X Qi, W Ren, V De Stefano, D Fan - Clinical Gastroenterology and …, 2014 - Elsevier
Background & Aims We conducted a systematic review and meta-analysis to evaluate the
associations of the coagulation factor V (encoded by F5) Leiden (FVL) or prothrombin …

Primary prevention of ischemic stroke: a statement for healthcare professionals from the Stroke Council of the American Heart Association

LB Goldstein, R Adams, K Becker, CD Furberg… - Stroke, 2001 - Am Heart Assoc
Stroke ranks as the third leading cause of death in the United States. It is now estimated that
there are more than 700000 incident strokes annually and 4.4 million stroke survivors. 1, 2 …

[HTML][HTML] Homocysteine, MTHFR and risk of venous thrombosis: a meta‐analysis of published epidemiological studies

M Den Heijer, S Lewington, R Clarke - Journal of Thrombosis and …, 2005 - Elsevier
Context: It has been suggested that elevated total plasma homocysteine levels are
associated with the risk of venous thrombosis. Objective: To assess the relationship of …

Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase …

B Simone, V De Stefano, E Leoncini, J Zacho… - European journal of …, 2013 - Springer
Genetic and environmental factors interact in determining the risk of venous
thromboembolism (VTE). The risk associated with the polymorphic variants G1691A of factor …

[HTML][HTML] Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians

H Refsum, CS Yajnik, M Gadkari, J Schneede… - The American journal of …, 2001 - Elsevier
ABSTRACT Background: In India, most people adhere to a vegetarian diet, which may lead
to cobalamin deficiency. Objective: The objective was to examine indicators of cobalamin …

The genetics of venous thromboembolism

R Gohil, G Peck, P Sharma - Thrombosis and haemostasis, 2009 - thieme-connect.com
We conducted a systematic and comprehensive meta-analysis on all candidate genes to
assess their genetic contribution to the aetiology of venous thromboembolism …

Genetic and acquired prothrombotic risk factors and sudden hearing loss

P Capaccio, F Ottaviani, V Cuccarini… - The …, 2007 - Wiley Online Library
Objectives: Idiopathic sudden sensorineural hearing loss (ISSNHL) is a frequently
encountered condition, and various pathogenetic mechanisms have been hypothesized …

American College of Medical Genetics consensus statement on factor V Leiden mutation testing

WW Grody, JH Griffin, AK Taylor, BR Korf… - Genetics in Medicine, 2001 - nature.com
When appropriate clinical care requires testing for the factor V Leiden allele, either direct
DNA-based genotyping or a factor V Leiden-specific functional assay is recommended …

[HTML][HTML] Primary habitual abortions are associated with high frequency of factor V Leiden mutation

ML Wramsby, M Sten-Linder, K Bremme - Fertility and sterility, 2000 - Elsevier
Objective: To analyze the prevalence of the mutation G1691A in factor V gene (Leiden
mutation), of mutation C677T in the methylenetetrahydrofolate reductase (MTHFR) gene …