Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …

Neuroinflammation is a normal and healthy response to neuronal damage. However,
excessive or chronic neuroinflammation exacerbates neurodegeneration after trauma and in …

The water permeability of aquaporin-11 (AQP11), which has a cysteine substituted for an
alanine at a highly conserved asparagine-proline-alanine (NPA) motif in the water channel …

Abstract Aquaporin-4 (AQP4) is essential for normal functioning of the brain's glymphatic
system. Impaired glymphatic function is associated with neuroinflammation. Recent clinical …

Water channel aquaporin 4 (AQP4) plays a key role in the regulation of water homeostasis
in the brain. It is predominantly expressed in astrocytes at the blood–brain and blood–liquor …

After injury to the spinal cord, edema contributes to the underlying detrimental
pathophysiological outcomes that lead to worsening of function. Several related membrane …

The aquaporin (AQP) family of integral membrane protein channels mediate cellular water
and solute flow. Although qualitative and quantitative differences in channel permeability …

Aquaporins (AQPs) can be revisited from a distinct and complementary perspective: the
outcome from analyzing them from both plant and animal studies.(1) The approach in the …

Aquaporin family comprises of transmembrane channels that are specialized in conducting
water and certain small, uncharged molecules across cell membranes. Essential roles of …

Aquaporins (AQPs) play a physiological role in several organs and tissues, and their
alteration is associated with disorders of water regulation. The identification of molecular …