European Association of Urology guidelines on testicular cancer: 2023 update

A Patrikidou, W Cazzaniga, D Berney, J Boormans… - European Urology, 2023 - Elsevier
Abstract Context Each year the European Association of Urology (EAU) produce a document
based on the most recent evidence on the diagnosis, therapy, and follow-up of testicular …

Advances in diagnosis and treatment of testicular cancer

M Chovanec, L Cheng - bmj, 2022 - bmj.com
Testicular cancer is a curable cancer. The success of physicians in curing the disease is
underpinned by multidisciplinary advances. Cisplatin-based combination chemotherapy and …

Testicular seminoma and non-seminoma: ESMO-EURACAN Clinical Practice Guideline for diagnosis, treatment and follow-up☆

J Oldenburg, DM Berney, C Bokemeyer… - Annals of …, 2022 - annalsofoncology.org
Germ-cell tumours (GCTs) affect predominantly younger males aged between 15 and 40
years, with nearly 74 500 new cases estimated globally in 2020. 1 About one-third of all GCT …

Testicular cancer in 2023: Current status and recent progress

DJ McHugh, JP Gleeson… - CA: A Cancer Journal for …, 2024 - Wiley Online Library
Testicular germ cell tumor (GCT) is the most common solid tumor in adolescent and young
adult men. Progress in the management of GCT has been made in the last 50 years, with a …

Targeting oncogenic microRNAs from the miR-371~ 373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle …

S Bailey, M Ferraresso, L Alonso-Crisostomo… - British Journal of …, 2023 - nature.com
Abstract Background MiR-371~ 373 and miR-302/367 cluster over-expression occurs in all
malignant germ cell tumours (GCTs), regardless of age (paediatric/adult), site …

Oncological treatments have limited effects on the fertility prognosis in testicular cancer: A systematic review and meta‐analysis

J Pape, J Fernando, D Megaritis, S Weidlinger… - …, 2024 - Wiley Online Library
Background Testicular cancer is the most common solid tumour among young men in the
reproductive phase. After completing cancer treatment, up to 77% of cancer survivors report …

Testicular cancer: biology to bedside

J King, N Adra, LH Einhorn - Cancer research, 2021 - AACR
Testicular cancer is the first solid tumor with a remarkably high cure rate. This success was
only made possible through collaborative efforts of basic and clinical research. Most patients …

Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium

A Fonseca, J Lobo, FK Hazard, J Gell… - British journal of …, 2022 - nature.com
Germ cell tumours (GCTs) are a heterogeneous group of rare neoplasms that present in
different anatomical sites and across a wide spectrum of patient ages from birth through to …

Cardiovascular disease in testicular cancer survivors: identification of risk factors and impact on quality of life

S Lubberts, HJ Groot, R de Wit, S Mulder… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Testicular cancer (TC) treatment is clearly associated with cardiovascular
morbidity and mortality. To enable development of preventive strategies for cardiovascular …

Chromosome 3p25. 3 gain is associated with cisplatin resistance and is an independent predictor of poor outcome in male malignant germ cell tumors

DM Timmerman, TF Eleveld, S Sriram… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Cisplatin is the main systemic treatment modality for male type II germ cell tumors
(GCTs). Although generally very effective, 5%-10% of patients suffer from cisplatin-resistant …