The invasiveness of cells is correlated with the presence of dynamic actin-rich membrane
structures called invadopodia, which are membrane protrusions that are associated with …

Abstract Poly (ethylene glycol)(PEG) hydrogels, modified with RGD, are promising platforms
for cell encapsulation and tissue engineering. While these hydrogels offer tunable …

Immune cells encounter tissues with vastly different biochemical and physical
characteristics. Much of the research emphasis has focused on the role of cytokines and …

The nucleus is mechanically coupled to the three cytoskeletal elements in the cell via
linkages maintained by the LINC complex (for Linker of Nucleoskeleton to Cytoskeleton). It …

Matrix-activated integrins can form different adhesion structures. We report that
nontransformed fibroblasts develop podosome-like adhesions when spread on fluid Arg-Gly …

Macrophages participate in immunity, tissue repair and tissue homeostasis. Activation of Toll-
like receptors (TLRs) by conserved exogenous or endogenous structures initiates signaling …

Cell mechanical activity generated from the interplay between the extracellular matrix (ECM)
and the actin cytoskeleton is essential for the regulation of cell adhesion, spreading and …

Assembly and disassembly of adhesion structures such as focal adhesions (FAs) and
podosomes regulate cell adhesion and differentiation. On antigen-presenting dendritic cells …

Cell migration profoundly influences cellular function, often resulting in adverse effects in
various pathologies including cancer metastasis. Directly assessing and quantifying the …

Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal
progression and post‐surgical recurrence and histologically by the accumulation of collagen …